Approaches to assessing the provider experience with clinical pharmacogenomic information: a scoping review
| Autor: | John P. Bentley, Tyler J Dunn, Meagen Rosenthal, Nicholas J. Keeling, James M. Hoffman, Sujith Ramachandran |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty business.industry Genetic counseling MEDLINE Pharmacist Medical laboratory 030105 genetics & heredity Article Clinical Practice 03 medical and health sciences 030104 developmental biology Pharmacogenomics Family medicine Medicine Clinical case Clinical care business Genetics (clinical) |
| Zdroj: | Genet Med |
| ISSN: | 1098-3600 |
| Popis: | PURPOSE: Barriers to the implementation of pharmacogenomics in clinical practice have been thoroughly discussed over the past decade. METHODS: The objective of this scoping review was to characterize the peer-reviewed literature surrounding the experiences and actions of prescribers, pharmacists, or genetic counselors when using pharmacogenomic information in real-world or hypothetical research settings. RESULTS: A total of 33 studies were included in the scoping review. The majority of studies were conducted in the US (70%), used quantitative or mixed methods (79%) with physician or pharmacist respondents (100%). The qualitative content analysis revealed five major methodological approaches: hypothetical clinical case scenarios, real-world studies evaluating prescriber response to recommendations or alerts, cross-sectional quantitative surveys, cross-sectional qualitative surveys/interviews, and a quasi-experimental real-world study. CONCLUSION: The findings of this scoping review can guide further research on the factors needed to successfully integrate pharmacogenomics into clinical care. |
| Databáze: | OpenAIRE |
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