MACROGLOBULINEMIA
| Autor: | Gerda van Leeuwen, Leonhard Korngold |
|---|---|
| Rok vydání: | 1957 |
| Předmět: |
Pathology
medicine.medical_specialty animal structures Globulin Immunology Article fluids and secretions Antigen Macroglobulins medicine Immunology and Allergy Antigens skin and connective tissue diseases biology Chemistry Macroglobulinemia Gamma globulin Ouchterlony double immunodiffusion Molecular biology Macroglobulin Immunoglobulin G embryonic structures biology.protein Serum Globulins gamma-Globulins Ultracentrifuge Waldenstrom Macroglobulinemia circulatory and respiratory physiology |
| Zdroj: | The Journal of Experimental Medicine |
| ISSN: | 1540-9538 0022-1007 |
| DOI: | 10.1084/jem.106.4.467 |
| Popis: | Highly purified pathological macroglobulins, which had been characterized electrophoretically and in the ultracentrifuge, were studied by the Ouchterlony gel diffusion technique. These macroglobulins were shown to be antigenically related to normal γ1-macroglobulin (19S) as well as the 7S γ-globulins. The pathological macroglobulins differ among each other and they are antigenically deficient when compared with the normal macroglobulin. There is no correlation between the macroglobulin's antigenic structure and its physico-chemical properties. |
| Databáze: | OpenAIRE |
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