Human Milk Microbiota: Transferring the Antibiotic Resistome to Infants

Autor:	Yogendra Singh, Lahari Das, Vishal Sharma, Richa Virmani, Deepti Rawat
Rok vydání:	2019
Předmět:	0106 biological sciences medicine.medical_specialty medicine.drug_class Antibiotics Population Review Article Breast milk Gut flora 01 natural sciences Microbiology digestive system 03 medical and health sciences Antibiotic resistance Medical microbiology fluids and secretions 010608 biotechnology medicine education 0303 health sciences education.field_of_study biology 030306 microbiology Transmission (medicine) biology.organism_classification Resistome
Zdroj:	Indian J Microbiol
ISSN:	0046-8991
Popis:	Commensal bacterial population is believed to be a reservoir for antibiotic resistance genes (ARGs). The infant gut microbiota has relatively higher abundance of ARGs than the adults. These genes can get transferred from commensals to pathogens by horizontal gene transfer, which magnifies the spectrum of antibiotic resistance in the environment. The presence of ARGs in neo-nates and infants, with no prior antibiotic exposure, questions their origin in the naive commensal population. Breast milk microbiota that is responsible for the initial seeding of infant gut microbiota has also been found to harbour a vast array of ARGs. This review discusses the recent findings that indicate the potential of breast milk microbiota to act as a vehicle for transmission of ARGs to infants.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e774e753d6428acda67744be70be7347 https://pubmed.ncbi.nlm.nih.gov/31762502 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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