Stem-cell-like T cells have a specific entry gate to the tumor

Autor: Werner, Held, Sanjiv A, Luther, Tatiana V, Petrova
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Cancer cell, vol. 40, no. 3, pp. 243-245
Popis: Tumor-infiltrated T cells with stem-cell-like properties are important for determining the immunotherapy response. In this issue of Cancer Cell, Asrir and colleagues show that their entry requires specialized tumor-associated endothelial cells that resemble immature and inflamed lymph node vessels and that immunotherapy enhances the recruitment capacity of these endothelial cells.
Databáze: OpenAIRE