A tribo-mechanical analysis of PVA-based building-blocks for implementation in a 2-layered skin model
| Autor: | Xiangqiong Zeng, E.G. de Vries, M. Morales Hurtado, E. van der Heide |
|---|---|
| Přispěvatelé: | Faculty of Engineering Technology |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Materials science
Friction Surface Properties Biomedical Engineering Biocompatible Materials 02 engineering and technology Polyvinyl alcohol Viscoelasticity Biomaterials 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Elastic Modulus Humans Composite material Elastic modulus chemistry.chemical_classification Skin Artificial METIS-320548 integumentary system Hydrogels Dynamic mechanical analysis Polymer Tribology 021001 nanoscience & nanotechnology chemistry Creep Mechanics of Materials Polyvinyl Alcohol Self-healing hydrogels IR-104162 0210 nano-technology |
| Zdroj: | Journal of the mechanical behavior of biomedical materials, 62, 319-332. Elsevier |
| ISSN: | 1751-6161 |
| DOI: | 10.1016/j.jmbbm.2016.05.001 |
| Popis: | Poly(vinyl) alcohol hydrogel (PVA) is a well-known polymer widely used in the medical field due to its biocompatibility properties and easy manufacturing. In this work, the tribo-mechanical properties of PVA-based blocks are studied to evaluate their suitability as a part of a structure simulating the length scale dependence of human skin. Thus, blocks of pure PVA and PVA mixed with Cellulose (PVA-Cel) were synthesised via freezing/thawing cycles and their mechanical properties were determined by Dynamic Mechanical Analysis (DMA) and creep tests. The dynamic tests addressed to elastic moduli between 38 and 50 kPa for the PVA and PVA-Cel, respectively. The fitting of the creep compliance tests in the SLS model confirmed the viscoelastic behaviour of the samples with retardation times of 23 and 16 seconds for the PVA and PVA-Cel, respectively. Micro indentation tests were also achieved and the results indicated elastic moduli in the same range of the dynamic tests. Specifically, values between 45–55 and 56–81 kPa were obtained for the PVA and PVA-Cel samples, respectively. The tribological results indicated values of 0.55 at low forces for the PVA decreasing to 0.13 at higher forces. The PVA-Cel blocks showed lower friction even at low forces with values between 0.2 and 0.07. The implementation of these building blocks in the design of a 2-layered skin model (2LSM) is also presented in this work. The 2LSM was stamped with four different textures and their surface properties were evaluated. The hydration of the 2LSM was also evaluated with a corneometer and the results indicated a gradient of hydration comparable to the human skin. |
| Databáze: | OpenAIRE |
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