Visual improvement in central retinal vein occlusion (CRVO) following intravitreal injections of bevacizumab (Avastin®)
| Autor: | Johann Gudmundsson, Gunvor von Wendt, Peep V. Algvere, Anders Kvanta, Stefan Seregard |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Vascular Endothelial Growth Factor A medicine.medical_specialty Intraocular pressure Visual acuity genetic structures Bevacizumab Visual Acuity Angiogenesis Inhibitors Antibodies Monoclonal Humanized Macular Edema Retina chemistry.chemical_compound Central retinal vein occlusion Ophthalmology Retinal Vein Occlusion medicine Humans Prospective Studies Fluorescein Angiography Prospective cohort study Intraocular Pressure Aged medicine.diagnostic_test business.industry Antibodies Monoclonal Retinal General Medicine Middle Aged Fluorescein angiography medicine.disease eye diseases Surgery chemistry Concomitant Intravitreal Injections Female sense organs medicine.symptom business Tomography Optical Coherence Follow-Up Studies medicine.drug |
| Zdroj: | Acta Ophthalmologica. 88:836-841 |
| ISSN: | 1755-375X |
| DOI: | 10.1111/j.1755-3768.2009.01758.x |
| Popis: | Acta Ophthalmol. 2010: 88: 836–841 Abstract. Purpose: To perform a prospective study on central retinal vein occlusion (CRVO) to evaluate whether visual acuity can be improved and macular oedema reduced in response to intravitreal injections of bevacizumab. Methods: The case material comprised 13 patients (aged 34–79 years), duration of CRVO was 2 weeks to 6 months, baseline ETDRS visual acuity 0.06–0.4 (mean Snellen 0.13, derived from logMAR value) and intraocular pressure (IOP) 12–20 (mean 15.2) mmHg. Clinical examination, including optical coherence tomography (OCT), was carried out at baseline and every 6 weeks, digital fluorescein angiography at baseline, at 3 months and 6 months. Intravitreal injections of bevacizumab (1.25 mg) were given under microscopic control at baseline and every 6 weeks during the 6-month follow-up. Results: Following one intravitreal injection of bevacizumab, average visual acuity improved by 13 ETDRS letters at 1 month (p |
| Databáze: | OpenAIRE |
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