Predictors and moderators of outcome for severe and enduring anorexia nervosa
| Autor: | Daniel Le Grange, Bryony Bamford, Stephen Touyz, Hubert Lacey, Ellen E. Fitzsimmons-Craft, Phillipa Hay, Ross D. Crosby, Colleen Stiles-Shields |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Employment medicine.medical_specialty Anorexia Nervosa Time Factors Experimental and Cognitive Psychology Outcome (game theory) law.invention Young Adult Quality of life Randomized controlled trial Risk Factors law medicine Humans Psychiatry Depression (differential diagnoses) Cognitive Behavioral Therapy Binge eating Depression Age Factors Middle Aged Protective Factors Mental health Psychotherapy Psychiatry and Mental health Clinical Psychology Mental Health Treatment Outcome Anorexia nervosa (differential diagnoses) Chronic Disease Quality of Life Female medicine.symptom Psychology Social Adjustment Follow-Up Studies Psychopathology Clinical psychology |
| Zdroj: | Behaviour Research and Therapy. 56:91-98 |
| ISSN: | 0005-7967 |
| DOI: | 10.1016/j.brat.2014.03.006 |
| Popis: | Few of the limited randomized controlled trials (RCTs) for adults with anorexia nervosa (AN) have explored predictors and moderators of outcome. This study aimed to identify predictors and moderators of outcome at end of treatment (EOT) and 6- and 12-month follow-up for adults with AN (N = 63). All participants met criteria for severe and enduring AN (duration of illness ≥ 7 years) and participated in an RCT of cognitive-behavioral therapy (CBT-AN) and specialist supportive clinical management (SSCM). General linear models were utilized and included all available outcome data at all time points. Outcome was assessed across three domains: eating disorder quality of life (EDQOL), mental health (MCS), and depressive symptoms (BDI). Predictors of better outcome included: lower age, shorter duration of illness, having AN-R, being employed, not taking psychotropic medication, and better social adjustment. Four moderators of treatment outcome emerged: eating disorder psychopathology (EDE Global), depression (BDI), age, and AN subtype. Participants with higher baseline scores on these measures, older age, or binge eating/purging subtype benefited more from CBT-AN than SSCM. Older patients with more severe eating-related psychopathology and depression have better outcomes in a behaviorally targeted treatment such as CBT-AN rather than a supportive treatment such as SSCM. |
| Databáze: | OpenAIRE |
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