Leukaemia inhibitory factor mediated proliferation of HTR-8/SVneo trophoblast cells is dependent on activation of extracellular signal-regulated kinase 1/2

Autor:	Pankaj Suman, Golla Jaya Prakash, Morales Prieto Dm, Udo R. Markert, Satish K. Gupta
Rok vydání:	2011
Předmět:	STAT3 Transcription Factor MAPK/ERK pathway endocrine system medicine.medical_specialty Time Factors Cell Survival Antigens Polyomavirus Transforming Apoptosis Stimulation Reproductive technology Biology Leukemia Inhibitory Factor Endocrinology Internal medicine Nitriles Butadienes Genetics medicine Extracellular Humans Phosphorylation STAT3 Protein Kinase Inhibitors Molecular Biology Cell Line Transformed Cell Proliferation bcl-2-Associated X Protein Mitogen-Activated Protein Kinase 1 Mitogen-Activated Protein Kinase 3 Cell Cycle Cell cycle Trophoblasts Cell biology Enzyme Activation Proto-Oncogene Proteins c-bcl-2 Reproductive Medicine embryonic structures STAT protein biology.protein RNA Interference Animal Science and Zoology Signal Transduction Developmental Biology Biotechnology
Zdroj:	Reproduction, Fertility and Development. 23:714
ISSN:	1031-3613
Popis:	Leukaemia inhibitory factor (LIF) is one of the cytokines that is indispensable for embryo implantation. The aim of the present study was to investigate the role of activation of extracellular signal-regulated kinase (ERK) 1/2 in LIF-mediated proliferation of HTR-8/SVneo cells. Stimulation of HTR-8/SVneo cells with LIF (50 ng mL–1) resulted in an increase in cell proliferation (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e758bf66d4b415cc7320f239483ee14a https://doi.org/10.1071/rd10315 Zobrazit plný text záznamu