Clinical relevance of Zika symptoms in the context of a Zika Dengue epidemic
Autor: | Anaika González Valdés, Alfredo Ruiz Lozano, Luis Gonzalez Alvarez, Manuel Ramirez Nodal, Francisco Gutiérrez García, Carlos R. Pérez Díaz, Humberto Guanche Garcell |
---|---|
Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
0301 basic medicine
myalgia Male Pediatrics Disease medicine.disease_cause Polymerase Chain Reaction Zika virus Dengue fever Dengue 0302 clinical medicine Epidemiology Medicine 030212 general & internal medicine Chikungunya Aged 80 and over biology Coinfection Zika Virus Infection lcsh:Public aspects of medicine Cuba General Medicine Middle Aged Rash Arthralgia Infectious Diseases Female medicine.symptom Adult Diarrhea medicine.medical_specialty Adolescent 030106 microbiology Context (language use) lcsh:Infectious and parasitic diseases 03 medical and health sciences Young Adult Humans lcsh:RC109-216 Epidemics Aged business.industry Public Health Environmental and Occupational Health lcsh:RA1-1270 Zika Virus Dengue Virus biology.organism_classification medicine.disease Cross-Sectional Studies Asthenia business |
Zdroj: | Journal of Infection and Public Health, Vol 13, Iss 2, Pp 173-176 (2020) |
ISSN: | 1876-0341 |
Popis: | Background: The clinical characteristics of the most frequent arbovirosis (Dengue, Zika, Chikungunya) are very similar, which is a diagnostic challenge for clinicians. Objective: To identify the presence of clinical characteristics related to Zika virus infection confirmed by the laboratory in patients during an epidemic of co-infection with Zika and Dengue viruses. Method: Cross-sectional descriptive study of patients with clinical - epidemiological suspicion of Zika virus infection, who were admitted in the Hospital “Joaquín Albarrán” (La Habana, Cuba), during June 1 to October 31 of 2017. Demographic and symptoms and signs were recorded. By PCR for Zika virus (in blood or urine) the disease was confirmed. Results: 1541 patients were studied. The most frequent symptoms and signs were rash (93.8%), pruritus (77.9%), arthralgia (60.0%), headache (50.8%), myalgia (46.1%), fever (34.7%), asthenia (31.7%), and conjunctivitis (27.9%). Zika virus infection was confirmed in 279 patients (18.1%). Greater frequency of arthralgia, asthenia, and diarrhea was demonstrated in Zika confirmed patients. Conclusion: Minor clinical relevance was observed in the symptoms or signs of arboviral disease to support the clinical diagnosis of Zika virus infections by clinician during a Zika-Dengue epidemic. The assessment of the temporality of the onset of Zika and Dengue symptoms of these infections is recommended to assist clinicians in the differential diagnosis. Keywords: Non-specific febrile syndrome, Zika, Infection, Clinical picture, Cuba |
Databáze: | OpenAIRE |
Externí odkaz: |