Clinical relevance of Zika symptoms in the context of a Zika Dengue epidemic

Autor: Anaika González Valdés, Alfredo Ruiz Lozano, Luis Gonzalez Alvarez, Manuel Ramirez Nodal, Francisco Gutiérrez García, Carlos R. Pérez Díaz, Humberto Guanche Garcell
Jazyk: angličtina
Rok vydání: 2020
Předmět:
0301 basic medicine
myalgia
Male
Pediatrics
Disease
medicine.disease_cause
Polymerase Chain Reaction
Zika virus
Dengue fever
Dengue
0302 clinical medicine
Epidemiology
Medicine
030212 general & internal medicine
Chikungunya
Aged
80 and over

biology
Coinfection
Zika Virus Infection
lcsh:Public aspects of medicine
Cuba
General Medicine
Middle Aged
Rash
Arthralgia
Infectious Diseases
Female
medicine.symptom
Adult
Diarrhea
medicine.medical_specialty
Adolescent
030106 microbiology
Context (language use)
lcsh:Infectious and parasitic diseases
03 medical and health sciences
Young Adult
Humans
lcsh:RC109-216
Epidemics
Aged
business.industry
Public Health
Environmental and Occupational Health

lcsh:RA1-1270
Zika Virus
Dengue Virus
biology.organism_classification
medicine.disease
Cross-Sectional Studies
Asthenia
business
Zdroj: Journal of Infection and Public Health, Vol 13, Iss 2, Pp 173-176 (2020)
ISSN: 1876-0341
Popis: Background: The clinical characteristics of the most frequent arbovirosis (Dengue, Zika, Chikungunya) are very similar, which is a diagnostic challenge for clinicians. Objective: To identify the presence of clinical characteristics related to Zika virus infection confirmed by the laboratory in patients during an epidemic of co-infection with Zika and Dengue viruses. Method: Cross-sectional descriptive study of patients with clinical - epidemiological suspicion of Zika virus infection, who were admitted in the Hospital “Joaquín Albarrán” (La Habana, Cuba), during June 1 to October 31 of 2017. Demographic and symptoms and signs were recorded. By PCR for Zika virus (in blood or urine) the disease was confirmed. Results: 1541 patients were studied. The most frequent symptoms and signs were rash (93.8%), pruritus (77.9%), arthralgia (60.0%), headache (50.8%), myalgia (46.1%), fever (34.7%), asthenia (31.7%), and conjunctivitis (27.9%). Zika virus infection was confirmed in 279 patients (18.1%). Greater frequency of arthralgia, asthenia, and diarrhea was demonstrated in Zika confirmed patients. Conclusion: Minor clinical relevance was observed in the symptoms or signs of arboviral disease to support the clinical diagnosis of Zika virus infections by clinician during a Zika-Dengue epidemic. The assessment of the temporality of the onset of Zika and Dengue symptoms of these infections is recommended to assist clinicians in the differential diagnosis. Keywords: Non-specific febrile syndrome, Zika, Infection, Clinical picture, Cuba
Databáze: OpenAIRE