Chronic opioid analgesic usage post-kidney transplantation and clinical outcomes
| Autor: | Fidel Barrantes, Satyarth Kulshrestha, Fu L. Luan, Milagros Samaniego |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Graft Rejection Male medicine.medical_specialty Disease Kidney Function Tests Postoperative Complications Risk Factors Internal medicine Humans Medicine Medical prescription Kidney transplantation Retrospective Studies Transplantation Kidney business.industry Graft Survival Retrospective cohort study Odds ratio Middle Aged Prognosis medicine.disease Kidney Transplantation Surgery Analgesics Opioid Hospitalization medicine.anatomical_structure Opioid Kidney Failure Chronic Female Chronic Pain business Follow-Up Studies Glomerular Filtration Rate medicine.drug |
| Zdroj: | Clinical Transplantation. 28:1041-1046 |
| ISSN: | 0902-0063 |
| Popis: | Chronic opioid usage (COU) is common among patients with end-stage renal disease (ESRD) qualified for kidney transplantation and associated with inferior post-transplant outcomes. The magnitude of COU after kidney transplantation and its impact on transplant outcomes remain unknown. We performed a single-center retrospective study aimed to describe the prevalence of COU during the first year, to identify the predictors of COU and to determine the impact of COU on post-transplant outcomes including the rates of hospitalization and acute rejection during the first year, as well as long-term patient and graft survival. Among 1045 kidney transplant patients, 119 (11.4%) had required continued outpatient prescription of opioid analgesics during the first year after kidney transplantation, mostly for non-surgery-related pain (85%). A positive history of COU prior to transplantation was the strongest predictor of COU in the first year post-transplantation (adjusted odds ratio [AOR] 4.31, p |
| Databáze: | OpenAIRE |
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