Effect of exercise on pain processing and motor output in people with knee osteoarthritis: a systematic review and meta-analysis
| Autor: | Bill Vicenzino, Siobhan M Schabrun, Esther J. Smits, Catherine Mailloux, Scott C Starkey, Hugo Massé-Alarie, Michelle Hall, Fiona Dobson, Melanie L Plinsinga, Paul W. Hodges |
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| Rok vydání: | 2020 |
| Předmět: |
Pain Threshold
0301 basic medicine medicine.medical_specialty Biomedical Engineering MEDLINE Electric Stimulation Therapy Osteoarthritis Quadriceps Muscle 03 medical and health sciences 0302 clinical medicine Rheumatology Internal medicine Threshold of pain medicine Humans Orthopedics and Sports Medicine 030203 arthritis & rheumatology Core (anatomy) business.industry Osteoarthritis Knee medicine.disease Confidence interval Exercise Therapy 030104 developmental biology Meta-analysis Orthopedic surgery Physical therapy business |
| Zdroj: | Osteoarthritis and Cartilage. 28:1501-1513 |
| ISSN: | 1063-4584 |
| DOI: | 10.1016/j.joca.2020.07.009 |
| Popis: | Summary Objective Guidelines recommend exercise as a core treatment for knee osteoarthritis. However, it is unclear how exercise affects measures of pain processing and motor function. The aim was to evaluate the effect of exercise on measures of pain processing and motor function in people with knee osteoarthritis. Methods We searched five electronic databases (MEDLINE, EMBASE, CINAHL, SCOPUS and Cochrane Central Register of Controlled Trials) for studies on knee osteoarthritis, of any design, evaluating pain processing and motor function before and after exercise. Data were pooled with random-effects meta-analysis. Study quality was assessed using the Downs and Black and quality of evidence was assessed using the GRADE. Results Eighteen studies were eligible and 16 were included. Following acute exercise, pressure pain threshold increased local to the study limb (standardised mean difference [95% confidence interval (CI)] 0.26, [0.02, 0.51], n = 159 from 5 studies), but there was no statistically significant change remote from the study limb (0.09, [-0.11, 0.29], n = 90 from 4 studies). Following an exercise program (range 5–12 weeks) there were no statistically significant changes in pressure pain threshold (local 0.23, [-0.01, 0.47], n = 218 from 8 studies; remote 0.33 [-0.13, 0.79], n = 76 from 4 studies), temporal pain summation (0.38 [-0.08, 0.85], n = 122 from 3 studies) or voluntary quadriceps muscle activation (4.23% [-1.84 to 10.30], n = 139 from 4 studies). Conclusion Very-low quality evidence suggests that pressure pain threshold increases following acute exercise. Very-low quality evidence suggests that pressure pain threshold, temporal pain summation or voluntary quadriceps activation do not change statistically significantly following exercise programs. |
| Databáze: | OpenAIRE |
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