Temporal trends in respiratory care and bronchopulmonary dysplasia in very preterm infants over a 10-year period in Spain

Autor: Alejandro, Avila-Alvarez, Carlos, Zozaya, Sonia, Pértega-Diaz, Manuel, Sanchez-Luna, Martin, Iriondo-Sanz, Maria Dolores, Elorza, Fermín, García-Muñoz Rodrigo, Elena García, Victori
Rok vydání: 2021
Předmět:
Zdroj: Archives of Disease in Childhood - Fetal and Neonatal Edition. 107:143-149
ISSN: 1468-2052
1359-2998
Popis: ObjectiveTo evaluate trends in respiratory care practices and bronchopulmonary dysplasia (BPD) among very preterm infants born in Spain between 2010 and 2019.Study designThis was a retrospective cohort study of data obtained from a national population-based database (SEN1500 network). Changes in respiratory care and BPD-free survival of infants with gestational age (GA) of 230–316 weeks and ResultsA total of 17 952 infants were included. In the second period, infants were less frequently intubated in the delivery room and during neonatal intensive care unit stay. This corresponded with an increase in use of non-invasive ventilation techniques. There were no significant differences between the periods in BPD-free survival or survival without moderate-to-severe BPD. After adjusting for covariates, the RR for the change per year was significant for the following variables: never intubated (RR 1.03, 95% CI 1.02 to 1.04); intubation in the delivery room (RR 0.98, 95% CI 0.97 to 0.99); use of nasal intermittent positive pressure ventilation (RR 1.08, 95% CI 1.05 to 1.11); and BPD-free survival (only in the group with the lowest GA; RR 0.98, 95% CI 0.97 to 0.99).ConclusionOur findings reveal significant changes in respiratory care practices between 2009 and 2019. Despite an increase in use of non-invasive respiratory strategies, BPD-free survival did not improve and even worsened in the group with the lowest GA (230–256).
Databáze: OpenAIRE