Calcaneous quantitative ultrasound measurements predicts vertebral fractures in idiopathic male osteoporosis
| Autor: | Csaba Horváth, Szilvia Mészáros, Edit Tóth, Éva Hosszú, Emoke Csupor, Viktória Ferencz |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male musculoskeletal diseases medicine.medical_specialty Bone density Osteoporosis Urology Risk Assessment Absorptiometry Photon Rheumatology Bone Density Predictive Value of Tests medicine Humans Aged Ultrasonography Femoral neck Bone mineral business.industry Odds ratio Middle Aged medicine.disease Osteopenia Bone Diseases Metabolic Calcaneus Fractures Spontaneous medicine.anatomical_structure Predictive value of tests Relative risk Spinal Fractures Radiology business |
| Zdroj: | Joint Bone Spine. 74:79-84 |
| ISSN: | 1297-319X |
| DOI: | 10.1016/j.jbspin.2006.04.008 |
| Popis: | Objectives: The aim of this study was to identify the differences in ultrasound bone variables (QUS) and to test the ability to discriminate male patients with and without vertebral fractures. Methods: We therefore measured broadband ultrasound attenuation (BUA) and speed of sound (SOS) matched for bone mineral density (BMD) and vertebral deformity in idiopathic male osteoporosis. Results: One hundred and seventeen men (age 56.6 range 27e78) were divided into three groups (osteoporosis n ¼ 25, osteopenia n ¼ 58 and age-matched control n ¼ 34) according to BMD T-score by WHO criteria. We found 66 patients (56%) with at least one vertebral deformity during the study. BMD and BUA did not differ, while SOS was lower in osteoporosis (p < 0.001) and control group (p < 0.001) between the patients with and without vertebral compression. Strong positive correlation was demonstrated between BUA and BMD (lumbar spine r ¼ 0.44, p < 0.001, femoral neck r ¼ 0.56, p < 0.001, radius r ¼ 0.40, p < 0.001), while similar association between SOS and BMD values was not shown. There was no relationship between the BUA and vertebral fracture risk (Odds ratio: 1.14 95% CI: 0.80e1.61). However, the relative risk of vertebral fracture by SOS was 1.56 (95% CI: 1.08e2.62). Adjusting for age and BMI the risk of vertebral fracture did not change (odds ratio for SOS 1.50 95% CI: 1.02e2.22). After adjustment for BMD SOS was still associated with fracture risk at all measured sites (odds ratio: 1.43, 95% CI: 1.02e2.22; 1.41, 95% CI: 1.02e2.17 and 1.32, 95% CI: 1.02e2.0). Conclusion: Our results suggest that BUA values are more closely related to density and structure while SOS values are able to predict fractures. |
| Databáze: | OpenAIRE |
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