Biofilms and coronaviruses reservoirs: a perspective review
| Autor: | Danielle da Silva Trentin, Rafael Gomes Von Borowski |
|---|---|
| Přispěvatelé: | Institut de Génétique et Développement de Rennes (IGDR), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Federal University of Health Sciences of Porto Alegre = Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
2019-20 coronavirus outbreak
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Highly pathogenic viruses coronaviruses [SDV]Life Sciences [q-bio] Pneumonia Viral bat Biology medicine.disease_cause Applied Microbiology and Biotechnology biofilm Microbiology 03 medical and health sciences microbial interaction Chiroptera medicine Animals Humans 030304 developmental biology Coronavirus Disease Reservoirs 0303 health sciences persistent infection Ecology 030306 microbiology Host (biology) SARS-CoV-2 Biofilm COVID-19 biochemical phenomena metabolism and nutrition medicine.disease [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology host Viral pneumonia Biofilms Minireview Viral persistence Food Science Biotechnology |
| Zdroj: | Applied and Environmental Microbiology Applied and Environmental Microbiology, American Society for Microbiology, 2021, 87 (18), pp.AEM0085921. ⟨10.1128/AEM.00859-21⟩ Applied and Environmental Microbiology, 2021, 87 (18), pp.AEM0085921. ⟨10.1128/AEM.00859-21⟩ |
| ISSN: | 0099-2240 1098-5336 |
| Popis: | International audience; Bats are a key reservoir of coronaviruses (CoVs), including the agent of the severe acute respiratory syndrome, SARS-CoV-2, responsible for the recent deadly viral pneumonia pandemic. However, understanding how bats can harbor several microorganisms without developing illnesses is still a matter under discussion. Viruses and other pathogens are often studied as stand-alone even though it is known that, in nature, they mostly live in multi-species associations called biofilms - both externally and within the host. Microorganisms in biofilms are enclosed by an extracellular matrix that confers protection and improves survival. Previous studies have shown that viruses can secondarily colonize preexisting biofilms, and viral biofilms have also been already described. In this review, we raise the perspective that CoVs can persistently infect bats due to occurrence in biofilm structures. This phenomenon potentially provides an optimal environment for non-pathogenic and well-adapted viruses to interact with the host, as well as for viral recombination. Biofilms can also enhance virion viability in extracellular environments, such as in fomites and aquatic sediments, allowing viral persistence and dissemination. Moreover, understanding CoVs biofilm lifestyle in reservoirs might contribute to explain several burning questions that remain unanswered including persistence and transmissibility by highly pathogenic emerging CoVs. |
| Databáze: | OpenAIRE |
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