Supplementation with sodium butyrate improves growth and antioxidant function in dairy calves before weaning
| Autor: | Alexander C.O. Evans, Lu Ma, D.P. Bu, Shengtao Gao, A La Teng Zhu La, Zhongtang Yu, Wenhui Liu |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Antioxidant medicine.medical_treatment Immune function Butyrate Biochemistry Feed conversion ratio 03 medical and health sciences chemistry.chemical_compound Rumen Animal science Antioxidant activity medicine Weaning lcsh:SF1-1100 chemistry.chemical_classification lcsh:Veterinary medicine Research 0402 animal and dairy science Sodium butyrate 04 agricultural and veterinary sciences 040201 dairy & animal science Calf 030104 developmental biology chemistry Propionate lcsh:SF600-1100 Animal Science and Zoology Fermentation lcsh:Animal culture Food Science Biotechnology |
| Zdroj: | Journal of Animal Science and Biotechnology, Vol 12, Iss 1, Pp 1-9 (2021) Journal of Animal Science and Biotechnology |
| ISSN: | 2049-1891 |
| DOI: | 10.1186/s40104-020-00521-7 |
| Popis: | Background There is increasing research interest in using short-chain fatty acids (SCFAs) including butyrate as potential alternatives to antibiotic growth promoters in animal production. This study was conducted to evaluate the effects of supplementation of sodium butyrate (SB) in liquid feeds (milk, milk replacer, and the mixture of both) on the growth performance, rumen fermentation, and serum antioxidant capacity and immunoglobins in dairy calves before weaning. Forty healthy female Holstein calves (4-day-old, 40 ± 5 kg of body weight) were housed in individual hutches and randomly allocated to 1 of 4 treatment groups (n = 10 per group) using the RAND function in Excel. The control group was fed no SB (SB0), while the other three groups were supplemented with 15 (SB15), 30 (SB30), or 45 (SB45) g/d of SB mixed into liquid feeds offered. The calves were initially fed milk only (days 2 to 20), then a mixture of milk and milk replacer (days 21 to 23), and finally milk replacer only (days 24 to 60). Results The SB supplementation enhanced growth and improved feed conversion into body weight gain compared with the SB0 group, and the average daily gain increased quadratically with increasing SB supplementation. No significant effect on rumen pH; concentrations of NH3-N, individual and total VFAs; or acetate: propionate (A:P) ratio was found during the whole experimental period. Serum glutathione peroxidase activity increased linearly with the increased SB supplementation, while the serum concentration of maleic dialdehyde linearly decreased. Serum concentrations of immunoglobulin A, immunoglobulin G, or immunoglobulin M were not affected by the SB supplementation during the whole experimental period. Conclusions Under the conditions of this study, SB supplementation improved growth performance and antioxidant function in pre-weaned dairy calves. We recommended 45 g/d as the optimal level of SB supplementation mixed into liquid feeds (milk or milk replacer) to improve the growth and antioxidant function of dairy calves before weaning. |
| Databáze: | OpenAIRE |
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