Unusual pattern in haemoglobin electrophoresis in Croatian population: a case report
| Autor: | Josip Batinić, Dunja Rogić, Dragana Šegulja, Danica Matišić, Lorena Honović |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Pediatrics
medicine.medical_specialty Croatia Anemia 030231 tropical medicine Clinical Biochemistry Population Case Report haemoglobinopathies 03 medical and health sciences 0302 clinical medicine HbE capillary zone electrophoresis Humans Medicine South east asian education education.field_of_study business.industry Hemoglobin E Public health Biochemistry (medical) Electrophoresis Capillary Infant Structural variant Globin chain University hospital medicine.disease 030220 oncology & carcinogenesis Haemoglobin electrophoresis business |
| Zdroj: | Biochemia Medica Volume 26 Issue 3 |
| ISSN: | 1846-7482 1330-0962 |
| Popis: | Haemoglobinopathies are hereditary disorders of globin chain synthesis and are the most common inherited diseases worldwide. Haemoglobin E is a structural haemoglobin variant characteristic for South East Asian population. We present a rare and unusual finding of haemoglobin E detected in University Hospital Centre Zagreb by capillary zone electrophoresis. Detection of haemoglobin structural variant helped to avoid misdiagnosis of sideropenic anemia and thus potentially harmful therapeutic intervention. In today’s European multiethnic population haemoglobinopathies are a public health issue and Croatian laboratory professionals should be aware of a possibility of finding an unusual haemoglobin pattern. |
| Databáze: | OpenAIRE |
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