Prevalence of Brugada sign in a Greek tertiary hospital population
| Autor: | Gerasimos Filippatos, Stavros P. Kounas, Gerasimos Gavrielatos, M Efremidis, Konstantinos P. Letsas, Antonios Sideris, Fotios Kardaras |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Adolescent Heart disease Population Hospital population Sudden cardiac death Electrocardiography Physiology (medical) Prevalence Humans Medicine cardiovascular diseases education Aged Brugada Syndrome Brugada syndrome Aged 80 and over education.field_of_study Greece business.industry Incidence (epidemiology) Clinical course Middle Aged Prognosis medicine.disease Hospitals Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Europace. 9:1077-1080 |
| ISSN: | 1532-2092 1099-5129 |
| DOI: | 10.1093/europace/eum221 |
| Popis: | AIMS The purpose of the present study was to determine for the first time the prevalence of Brugada-type electrocardiographic (ECG) pattern (Brugada sign) in unselected individuals served by an urban Greek tertiary hospital during a 4-year time period. METHODS AND RESULTS Among 11,488 individuals (6640 males, 4848 females), 25 (23 males, 2 females, aged 36.8 +/- 19.2 years) were found to display the Brugada sign (0.22%). Two cases exhibited the diagnostic type 1 ECG pattern (0.02%) and 23 subjects fulfilled the ECG criteria for type 2 or 3 patterns (0.2%). The incidence of Brugada sign was higher among men (0.34%) than in women (0.04%). Structural heart disease was established in four cases (one of them exhibiting a type 1 ECG pattern). Twenty-one individuals (19 males, 2 females, aged 29.7 +/- 10.7 years) without structural heart disease displaying Brugada-type ECG features (4 cases with spontaneous or procainamide-induced type 1 ECG pattern) were subsequently selected and closely followed up for 24 +/- 12 months. No mortality or life-threatening ventricular arrhythmias were recorded during this period. CONCLUSION The Brugada-type ECG pattern is infrequently seen in a Greek hospital-based population. All subjects with Brugada sign and structurally normal hearts displayed a benign clinical course without arrhythmic events during a relatively long follow-up period. |
| Databáze: | OpenAIRE |
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