Self-report of psychological symptoms in hypoparathyroidism patients on conventional therapy
| Autor: | Marcos Assad, Ileana Borsato Bini, Maicon Piana Lopes, Victor Borsani S. Cury, Amanda J. Arneiro, Rodrigo Melo Kulchetscki, Breno S. Kliemann, G.L. Biagini, Victoria Zeghbi Cochenski Borba, Bianca C. C. Duarte, Carolina Aguiar Moreira |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty psychopathological symptoms Hypoparathyroidism Endocrinology Diabetes and Metabolism lcsh:Medicine Parathyroid hormone 030209 endocrinology & metabolism Reference range lcsh:Diseases of the endocrine glands. Clinical endocrinology Cohort Studies 03 medical and health sciences 0302 clinical medicine psychological distress Quality of life Internal medicine Surveys and Questionnaires medicine parathyroid hormone Outpatient clinic Humans Self report lcsh:RC648-665 business.industry lcsh:R Middle Aged medicine.disease SCL-90-R 030104 developmental biology Cross-Sectional Studies Case-Control Studies Cohort Quality of Life Female Self Report business Psychopathology |
| Zdroj: | Archives of Endocrinology and Metabolism v.62 n.3 2018 Arquivos de Endocrinologia e Metabolismo Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) instacron:SBEM Archives of Endocrinology and Metabolism, Volume: 62, Issue: 3, Pages: 319-324, Published: 17 MAY 2018 Archives of Endocrinology and Metabolism, Issue: ahead, Published: 17 MAY 2018 Archives of Endocrinology and Metabolism, Vol 62, Iss 3, Pp 319-324 (2018) |
| ISSN: | 2359-4292 |
| Popis: | Objective: Hypoparathyroidism is characterized by parathyroid hormone deficiency and hypocalcemia. It has been demonstrated that these patients may also present psychiatric symptoms and decrease of quality of life. The aims of this study were to evaluate the presence of psychopathological symptoms in a cohort of patients with hypoparathyroidism and compare to a control group. Subjects and methods: Patients were submitted to a cross-sectional Symptom Checklist-90-R (SCL-90-R) questionnaire that evaluates psychopathological symptoms by means of the Global Severity Index (GSI), Positive Symptoms Total (PST) and Positive Symptom Distress Index (PSDI). A score based in the positive symptoms was calculated (T-score). The test group was composed of patients with hypoparathyroidism, and control by thyroidectomized patients without hypoparathyroidism. A correlation between the presence of psychological symptoms and clinical features was analyzed. Results: The study included 57 patients with a mean age of 51.1 ± 16.4 years; 20 as a control and 37, test group. There were no differences between groups regarding gender, mean age and age at diagnose. Hypoparathyroidism patients presented higher GSI index than the control group (p = 0.038). Mean T-score of the test group was as elevated as 58.2 ± 5.3 (reference range < 55). No correlation of the number of psychological symptoms to clinical and laboratorial parameters was observed. Conclusion: Patients with hypoparathyroidism attending our outpatient clinics presented an increase in the number of self-report of psychological symptoms when compared with a control group. However, no correlation with hypocalcemia and clinical parameters was observed. Future studies are necessary to evaluated if the absence of PTH play a role on it. |
| Databáze: | OpenAIRE |
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