High incidence of preeclamptic toxemia in patients with polycystic ovarian disease
| Autor: | E. Rimon, Y.Z. Diamant, S. Evron |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent media_common.quotation_subject medicine.medical_treatment Ovulation Induction Pre-Eclampsia Pregnancy Humans Medicine Ovulation Preeclamptic toxemia media_common Gynecology business.industry Obstetrics Incidence (epidemiology) Hyperandrogenism Obstetrics and Gynecology Middle Aged medicine.disease Polycystic ovarian disease Pregnancy Complications Reproductive Medicine Androgens Female Ovulation induction business Polycystic Ovary Syndrome Hormone |
| Zdroj: | European Journal of Obstetrics & Gynecology and Reproductive Biology. 14:199-204 |
| ISSN: | 0301-2115 |
| DOI: | 10.1016/0028-2243(82)90097-1 |
| Popis: | The incidence of preeclamptic toxemia (PET) was investigated in 72 anovulatory, oligomenorrheic and previously nulliparous women who conceived after an induction of ovulation. One-thousand consecutive spontaneous pregnancies and 1,000 pregnancies of primiparae were used as control groups. The anovulatory group consisted of 33 consecutive well-documented cases of polycystic ovarian disease (PCO) and 39 anovulatory patients in whom PCO was excluded (A-NPCO). The results indicate that pregnancies after induction of ovulation are accompanied with a higher incidence of PET. The rate of this disorder was significantly higher in PCO groups than in A-NPCO women (28.5 vs. 4%), when calculated per number of all pregnancies. The difference between the incidence of PET in PCO, A-NPCO, control primiparae and normal control patients was even more pronounced when calculated on the basis of the number of patients (54.5, 12.5, 11 and 2.5%, respectively). Overproduction of steroid hormones, especially androgens, was suggested as the main factor for the appearance of PET in PCO patients. |
| Databáze: | OpenAIRE |
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