Serum Zinc and Selenium in Children with Inflammatory Bowel Disease: A Multicenter Study in Japan

Autor: Michiko Takahashi, Yuri Etani, Hirotaka Sakaguchi, Jun Ishihara, Toshihiko Kakiuchi, Ryusuke Nambu, Ken-Ichiro Konishi, Hitoshi Tajiri, Yushiro Yamashita, Tsuyoshi Sogo, Ryosuke Yasuda, Tatsuyuki Kakuma, Tomoki Aomatsu, Naoki Abe, Katsuhiro Arai, Kunio Hashimoto, Hitoshi Obara, Takahiro Kudo, Tatsuki Mizuochi
Rok vydání: 2021
Předmět:
Zdroj: Digestive Diseases and Sciences. 67:2485-2491
ISSN: 1573-2568
0163-2116
Popis: Reports of zinc and selenium deficiencies accompanying inflammatory bowel disease (IBD) mostly have originated from Western countries and concerned adult patients. Whether Japanese children with IBD have similar deficiencies remained unclear. We aimed to elucidate differences in serum zinc and selenium concentrations in Japanese children between types of IBD. Children under 17 years old undergoing care at 12 Japanese pediatric centers were retrospectively enrolled between November 2016 and February 2018 to 3 groups representing Crohn’s disease (CD), ulcerative colitis (UC), and normal controls (NC) with irritable bowel syndrome or no illnesses. Serum zinc and selenium were measured by atomic absorption spectrophotometry. Zinc and selenium deficiencies were defined by serum concentrations
Databáze: OpenAIRE