The Coordination Chemistry of Bio-Relevant Ligands and Their Magnesium Complexes
| Autor: | Jon Zubieta, Derek R. Case, Robert P. Doyle |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
030309 nutrition & dietetics
Pharmaceutical Science chemistry.chemical_element Review Ligands 010402 general chemistry 01 natural sciences Dietary Magnesium Analytical Chemistry Coordination complex Hypomagnesemia lcsh:QD241-441 hypomagnesemia 03 medical and health sciences lcsh:Organic chemistry Magnesium deficiency (medicine) Drug Discovery medicine Humans Magnesium Chelation Physical and Theoretical Chemistry Chelating Agents nutraceuticals chemistry.chemical_classification 0303 health sciences Organic Chemistry medicine.disease Combinatorial chemistry 0104 chemical sciences chelates chemistry Chemistry (miscellaneous) coordination chemistry Molecular Medicine Magnesium Deficiency |
| Zdroj: | Molecules Molecules, Vol 25, Iss 3172, p 3172 (2020) |
| ISSN: | 1420-3049 |
| Popis: | The coordination chemistry of magnesium (Mg2+) was extensively explored. More recently; magnesium; which plays a role in over 80% of metabolic functions and governs over 350 enzymatic processes; is becoming increasingly linked to chronic disease—predominantly due to magnesium deficiency (hypomagnesemia). Supplemental dietary magnesium utilizing biorelevant chelate ligands is a proven method for counteracting hypomagnesemia. However, the coordination chemistry of such bio-relevant magnesium complexes is yet to be extensively explored or elucidated. It is the aim of this review to comprehensively describe what is currently known about common bio-relevant magnesium complexes from the perspective of coordination chemistry. |
| Databáze: | OpenAIRE |
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