Evaluation of Methods to Determine Excessive Decline of Forced Expiratory Volume in One Second in Workers Exposed to Diacetyl-Containing Flavorings
| Autor: | Paul L. Enright, Artak Hakobyan, Eva Hnizdo, Neal F. Chaisson, Kathleen Kreiss |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Lung Diseases Male Risk Spirometry Gerontology medicine.medical_specialty Adolescent Data variability Diacetyl Cohort Studies Occupational medicine Young Adult Forced Expiratory Volume Occupational Exposure Internal medicine medicine Humans Occupations Aged Aged 80 and over Alternative methods medicine.diagnostic_test business.industry Incidence (epidemiology) Arizona Public Health Environmental and Occupational Health Reproducibility of Results Middle Aged Occupational Diseases Relative risk Cohort Disease Progression Female business Cohort study |
| Zdroj: | Journal of Occupational & Environmental Medicine. 52:1119-1123 |
| ISSN: | 1076-2752 |
| DOI: | 10.1097/jom.0b013e3181f84577 |
| Popis: | Objective: To evaluate methods for determining excessive short-term decline in forced expiratory volume in one second (FEV 1 ) in diacetyl-exposed workers. Methods: We evaluated five methods of determining excessive longitudinal FEV 1 decline in diacetyl-exposed workers and workers from a comparative cohort: American Thoracic Society (ATS), ACOEM an 8% limit, and a relative and absolute longitudinal limit on the basis of spirometry data variability. Relative risk and incidence of excess decline were evaluated. Results: Incidence of excessive FEV 1 decline was 1% in the comparative cohort using ATS and ACOEM criteria, 4.1% using relative limit of longitudinal decline, 4.4% with absolute longitudinal limit of decline, and 5.6% by using the 8% limit. Relative risk of abnormal FEV 1 decline in diacetyl-exposed workers was elevated in all evaluated methods. Conclusion: Alternative methods for respiratory surveillance in diacetyl-exposed workers may be preferable to ATS or ACOEM. |
| Databáze: | OpenAIRE |
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