Additional file 1 of Radiolabeling and PET–MRI microdosing of the experimental cancer therapeutic, MN-anti-miR10b, demonstrates delivery to metastatic lesions in a murine model of metastatic breast cancer

Autor: Le Fur, Mariane, Ross, Alana, Pantazopoulos, Pamela, Rotile, Nicholas, Zhou, Iris, Caravan, Peter, Medarova, Zdravka, Yoo, Byunghee
Rok vydání: 2021
DOI: 10.6084/m9.figshare.14936475.v1
Popis: Additional file 1: Figure S1. Time–activity curves obtained from PET images from 5 min to 48 h post-injection in a heart, b kidney and c liver from mice (n = 3) that were administered a microdose of 64Cu-MN-anti-miR10b. Error bars represent the standard deviation. Figure S2. Biodistribution of 64Cu-MN-anti-miR10b injected at a microdose and a standard therapeutic dose (macrodose) measured at a 24 and b 48 h after injection. #Denotes organs with metastasis as detected by BLI. Results are expressed as %ID/g. Error bars represent the standard deviation. (t-test, *P
Databáze: OpenAIRE