High-resolution inter-ictal SPET and phasedarray MRI in partial epilepsy
| Autor: | Alan J. Wilensky, Wendy A. Cohen, D. H. Lewis, Michelle D. Holmes, J. Schneider, Linda M. Ojemann, George A. Ojemann, P. Ory |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
Male Time Factors Adolescent Electroencephalography Temporal lobe Epilepsy Epilepsy Complex Partial Technetium Tc 99m Exametazime Neuroimaging medicine Humans Radiology Nuclear Medicine and imaging Ictal Cysteine Cerebral perfusion pressure Aged medicine.diagnostic_test business.industry Videotape Recording Magnetic resonance imaging Organotechnetium Compounds General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Temporal Lobe Treatment Outcome medicine.anatomical_structure Epilepsy Temporal Lobe Scalp Female Epilepsies Partial Radiopharmaceuticals Nuclear medicine business Follow-Up Studies Tomography Emission-Computed |
| Zdroj: | Nuclear Medicine Communications. 19:199-206 |
| ISSN: | 0143-3636 |
| DOI: | 10.1097/00006231-199803000-00003 |
| Popis: | To assess the clinical utility of high-resolution inter-ictal single photon emission tomography (SPET) of regional cerebral perfusion and high-resolution magnetic resonance imaging (MRI) of the brain with a phased-array temporal lobe coil, 35 patients with presumed partial epilepsy were evaluated prospectively by these techniques in addition to prolonged video/electroencephalographic (EEG) monitoring. Twenty of these patients had surgical treatment of partial epilepsy with outcome determinations spanning from 12 months to 3 years at follow-up. There were four categories of imaging findings as compared to scalp/sphenoidal EEG localization. Category I included 12 patients (34% of total) in whom there was complete imaging and EEG concordance. Category II included 4 patients (11 %) in whom MRI and EEG were concordant but SPET was divergent or normal. Category III included 13 patients (37%) in whom SPET and EEG were concordant but MRI was divergent or normal. Category IV included 4 patients (11%) in whom neither SPET nor MRI was concordant with EEG. In this study, the relative sensitivities of SPET and MRI for localization of partial epilepsy based on prolonged scalp/sphenoidal video/EEG recordings were 76% and 49%, respectively. We conclude that these neuroimaging techniques (phased-array MRI and inter-ictal cerebral perfusion SPET) are complementary and useful in the pre-operative evaluation of patients with partial epilepsy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|