Novel genetic variation associated to CSN3 strongly affects rennet-induced milk coagulation
| Autor: | Lone Bruhn Madsen, Vivi Raundahl Gregersen, G.M. Maciel, Mikka Stenholdt Hansen, Lotte Bach Larsen, Bart Buitenhuis, Christian Bendixen, Nina Aagaard Poulsen |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Genetics Coagulation time Haplotype 0402 animal and dairy science Genetic variants food and beverages 04 agricultural and veterinary sciences Biology 040201 dairy & animal science Applied Microbiology and Biotechnology Casein micelles 03 medical and health sciences 030104 developmental biology Coagulation Genetic variation Rennet Food science Food Science Total protein |
| Zdroj: | Poulsen, N A, Gregersen, V R, Maciel, G D M, Madsen, L B, Buitenhuis, A J, Stenholt Hansen, M, Bendixen, C & Larsen, L B 2017, ' Novel genetic variation associated to CSN3 strongly affects rennet-induced milk coagulation ', International Dairy Journal, vol. 71, pp. 122-130 . https://doi.org/10.1016/j.idairyj.2017.03.012 |
| DOI: | 10.1016/j.idairyj.2017.03.012 |
| Popis: | The effect on rennet-induced milk coagulation of three novel genetic haplotypes in close proximity to CSN3 encoding κ-casein was evaluated. Milk samples were collected from 71 Danish Holstein cows homozygous for the three novel haplotypes named according to which genetic variants of CSN3 they were characterised by: AE, A and B, respectively. The results documented that haplotype AE had significantly longer rennet coagulation time and lower curd firming rate compared with haplotypes A and B. Haplotype AE milk was further characterised by larger casein micelles and lower relative content of κ-casein, whereas the total protein contents did not differ among haplotypes. These findings indicate that the genetic κ-casein A variant can be divided into two groups with poor and good milk coagulation properties. Furthermore, three milk samples were identified as non-coagulating. These were all associated with the haplotype AE. |
| Databáze: | OpenAIRE |
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