Genome-wide scans for detecting the selection signature of the Jeju-island native pig in Korea
| Autor: | Kyeong-Hye Won, Ki-Duk Song, Donghyun Shin, Sang Chul Lee, Young-Sup Lee, Dae Cheol Kim |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Linkage disequilibrium
Berkshire Pig Genetic stability Population lcsh:Animal biochemistry Biology Genome Article Linkage Disequilibrium 03 medical and health sciences Jeju Island Native Pig Yorkshire Pig education lcsh:QP501-801 Selection (genetic algorithm) 030304 developmental biology lcsh:SF1-1100 0303 health sciences Genetic diversity education.field_of_study 0402 animal and dairy science 04 agricultural and veterinary sciences Animal Breeding and Genetics 040201 dairy & animal science Population Differentiation Statistic Evolutionary biology Selection Signatures Yorkshire pig Animal Science and Zoology lcsh:Animal culture Selective sweep Food Science |
| Zdroj: | Asian-Australasian Journal of Animal Sciences Asian-Australasian Journal of Animal Sciences, Vol 33, Iss 4, Pp 539-546 (2020) |
| ISSN: | 1976-5517 1011-2367 |
| Popis: | Objective: The Jeju native pig (JNP) found on the Jeju Island of Korea is a unique black pig known for high-quality meat. To investigate the genetic uniqueness of JNP, we analyzed the selection signature of the JNP in comparison to commercial pigs such as Berkshire and Yorkshire pigs.Methods: We surveyed the genetic diversity to identify the genetic stability of the JNP, using the linkage disequilibrium method. A selective sweep of the JNP was performed to identify the selection signatures. To do so, the population differentiation measure, Weir-Cockerham’s Fst was utilized. This statistic directly measures the population differentiation at the variant level. Additionally, we investigated the gene ontologies (GOs) and genetic features.Results: Compared to the Berkshire and Yorkshire pigs, the JNP had lower genetic diversity in terms of linkage disequilibrium decays. We summarized the selection signatures of the JNP as GO. In the JNP and Berkshire pigs, the most enriched GO terms were epithelium development and neuron-related. Considering the JNP and Yorkshire pigs, cellular response to oxygen-containing compound and generation of neurons were the most enriched GO.Conclusion: The selection signatures of the JNP were identified through the population differentiation statistic. The genes with possible selection signatures are expected to play a role in JNP’s unique pork quality. |
| Databáze: | OpenAIRE |
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