The Relationship of Undifferentiated Mesenchymal Cells to TMJ Articular Tissue Thickness
| Autor: | C.A. Bibb, Andrew G. Pullinger, F. Baldioceda |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Adult
Cartilage Articular Male 0301 basic medicine Pathology medicine.medical_specialty Adolescent Condyle 03 medical and health sciences 0302 clinical medicine Temporal bone medicine Humans Progenitor cell General Dentistry Connective Tissue Cells Temporomandibular Joint Chemistry Stem Cells Cartilage Mesenchymal stem cell Mandibular Condyle Temporal Bone 030206 dentistry Anatomy Adaptation Physiological Sagittal plane Temporomandibular joint 030104 developmental biology medicine.anatomical_structure Female Stem cell |
| Zdroj: | Journal of Dental Research. 71:1816-1821 |
| ISSN: | 1544-0591 0022-0345 |
| Popis: | Undifferentiated mesenchymal (UM) cells, the progenitor cells of the cartilage layer, have been assigned a significant role in TMJ articular tissue maintenance. This was based on reports of UM cell reduction with increased soft-tissue thickness for the condyle and temporal component. However, the strength of this inverse relationship was not presented and remained unclear. The purpose of the present study was to assess the strength of the correlation between UM cell presence and soft-tissue thickness in young adult TMJs at autopsy. Sagittal histological sections from the central thirds of 50 joints were evaluated with respect to articular soft-tissue thickness, histological character, and UM cell presence in the condyle and temporal component. The superior sector ofthe condyle and the articular eminence showed the greatest variability in soft-tissue thickness and were the only areas to show localized UM cell absence. The eminence was the only location to show an inverse relationship between soft-tissue thickness and UM cell presence, and this was consistent in both an ANOVA (p = 0.0016) and a Spearman correlation analysis. However, the strength of this correlation was only moderate (rho = -0.52), and no such relationship was observed in any other location. This study suggests that the relationship between UM cell presence and soft-tissue thickness is more complex than previously hypothesized and that the contribution of UM cells to articular tissue maintenance has been overstated, while other biological processes were overlooked. |
| Databáze: | OpenAIRE |
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