Colonoscopic perforations in inflammatory bowel disease: a retrospective study in a French referral centre
| Autor: | Jean-Baptiste Chevaux, Laurent Peyrin-Biroulet, Anthony Buisson, Laurent Bresler, Marc-André Bigard, Hervé Hudziak |
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| Přispěvatelé: | Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Institut National de la Recherche Agronomique (INRA)-Université d'Auvergne - Clermont-Ferrand I (UdA), Nutrition-Génétique et Exposition aux Risques Environnementaux (NGERE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Service d'Hépato-Gastro-Entérologie, CHU Estaing [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, Service d'Hépato-gastro-entérologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Service de Chirurgie Digestive Hépatobiliaire et Endocrine [CHRU Nancy], Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte - Clermont Auvergne (M2iSH), Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne (UCA)-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne) |
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Colon [SDV]Life Sciences [q-bio] Perforation (oil well) Rectum Colonoscopy Inflammatory bowel disease Gastroenterology Cohort Studies 03 medical and health sciences Colonic Diseases Young Adult 0302 clinical medicine Crohn Disease Colon Sigmoid Internal medicine medicine Humans Aged Retrospective Studies Aged 80 and over Perforation Hepatology medicine.diagnostic_test business.industry Sigmoid colon Retrospective cohort study Diverticulitis Middle Aged medicine.disease Ulcerative colitis digestive system diseases 3. Good health Surgery medicine.anatomical_structure Intestinal Perforation 030220 oncology & carcinogenesis Case-Control Studies 030211 gastroenterology & hepatology Colitis Ulcerative Female France business |
| Zdroj: | Digestive and Liver Disease Digestive and Liver Disease, Elsevier, 2013, 45 (7), pp.569-572. ⟨10.1016/j.dld.2012.11.012⟩ Digestive and Liver Disease, WB Saunders, 2013, 45 (7), pp.569-572. ⟨10.1016/j.dld.2012.11.012⟩ |
| ISSN: | 1878-3562 1590-8658 |
| DOI: | 10.1016/j.dld.2012.11.012⟩ |
| Popis: | Background Whether inflammatory bowel disease patients are at increased risk of colonoscopic perforations remains controversial. Aim of this study was to investigate whether these patients are at increased risk of perforations. Methods Electronic charts of all patients enrolled in the Nancy IBD cohort (1999–2012) were reviewed. All non-inflammatory bowel disease patients who underwent colonoscopy (1999–2012) were used as controls. Results Of 17,992 colonoscopies, 2375 (13.2%) were performed for inflammatory bowel disease: 1547 for Crohn's disease and 828 for ulcerative colitis. Four IBD patients (0.168%) experienced perforation. Perforation occurred in the sigmoid colon (n = 3) and right colon (n = 1) during disease monitoring or colonic stenosis dilatation. Three patients underwent surgery (2 stomas and no death). Colonoscopic perforation occurred in 16/15,617 controls (0.102%): colonic cancer diagnosis (n = 5, 31.3%) or dilatation (n = 2, 12.5%), polypectomy (n = 5, 31.3%) or mucosectomy (n = 1, 6.3%), and follow-up after diverticulitis (n = 2, 12.5%). Perforation rate was not different between IBD and controls (p = 0.57). Perforations occurred in the sigmoid colon (n = 10, 62.5%), the right colon (n = 4, 25%) and the rectum (n = 2, 12.5%). Twelve controls underwent surgery (9 stomas and one death). Conclusion In this referral centre-based cohort, inflammatory bowel disease patients were not at increased risk of colonoscopic perforation compared to non-IBD controls. |
| Databáze: | OpenAIRE |
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