Influence of added cholesterol and dihydrocholesterol upon the multiplication of entamoeba histolytica in MS-F medium
| Autor: | Swartzwelder Jc, Cedillos Ra, Reeves Re |
|---|---|
| Rok vydání: | 1961 |
| Předmět: |
medicine.drug_class
Immunology Antibiotics Biology Microbiology chemistry.chemical_compound Entamoeba histolytica parasitic diseases medicine Cholesterol metabolism Cottonseed oil Strain (chemistry) Cholesterol General Medicine biology.organism_classification Pathogenicity Lipid Metabolism Culture Media Cholestanol Infectious Diseases chemistry Biochemistry Streptomycin Parasitology medicine.drug |
| Zdroj: | Experimental parasitology. 11 |
| ISSN: | 0014-4894 |
| Popis: | The influences of added dihydrocholesterol or cholesterol upon the growth of nine strains of Entamoeba histolytica in MS-F culture were investigated. Dihydrocholesterol was found to be strongly growth inhibitory to three strains, less so to five, and to have no observed effect upon one strain. Added cholesterol was strongly inhibitory to one, had a smaller adverse effect on five, and no observed effect upon three strains. The growth-inhibitory effect of dihydrocholesterol is not regarded as being due to its interfering with cholesterol metabolism since the strains which were most affected by the former were also inhibited by the latter. A variety of steroids, but not cottonseed oil or methyl oleate, was found to repress the growth of the DKB strain of E. histolytica. A possible relationship between dihydrocholesterol sensitivity and pathogenicity of amebae is discussed. Importance of the past history of an ameba culture and the need for greater detail in defining ameba cultures are stressed. |
| Databáze: | OpenAIRE |
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