Pregnancy with giant ovarian dysgerminoma
| Autor: | Dong-Wei Huang, Shu-Yan Liu, Zhen-De Jiang, Xi-Wen Zhang, Tong Yu, Li-Rong Zhai, Manhua Cui |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Abdominal pain medicine.medical_specialty medicine.medical_treatment media_common.quotation_subject MEDLINE Fertility Dysgerminoma chemotherapy surgery 03 medical and health sciences 0302 clinical medicine Pregnancy medicine Humans Clinical Case Report 030212 general & internal medicine media_common Ovarian Neoplasms Chemotherapy pregnancy outcome treatment Cesarean Section business.industry General surgery General Medicine medicine.disease malignant germ cell tumor 030220 oncology & carcinogenesis Vomiting Gestation Female medicine.symptom business Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 0025-7974 |
| DOI: | 10.1097/md.0000000000021214 |
| Popis: | Rationale: Dysgerminoma is an extraordinarily rare neoplasm arising from the malignant germ cells of the ovary. Early antenatal diagnosis and proper management of the neoplasm to improve maternal-neonatal results are the considerable challenges facing the gyne-oncologist. We summarize the clinical features and discuss treatment strategies of the ovary dysgerminoma (OD). Besides, we also review the literature on OD in PubMed, Web of Science Core Collection, Library of Congress, and LISTA from 1939 to 2019 to evaluate its clinical characteristics, feto-maternal compromise, management, and fertility outcome. Patient concerns: A 25-year-old pregnant woman reported lower abdominal pain and vomiting. Diagnosis: The patient was diagnosed as right OD. Interventions: She received a cesarean section due to severe abdominal pain, delivered a healthy girl at 38 C 4 weeks of gestation, and accepted fertility-preserving surgery. However, the patient refused chemotherapy postoperatively. Outcomes: The patient was followed up 42 days, 3 months, and 6 months after surgery, and no tumor recurrence was observed. Lessons: OD has non-specificity characteristics, including age, symptoms, image date, and tumor marks. However, these abnormal indicators may provide some evidence for accurate antenatal diagnosis. The management strategies should be considered comprehensively on an individual basis, and fertility-preserving surgery should be carried out in the second trimester if further pregnancy is desired. Adjuvant chemotherapy needs to be applied to the treatment of OD patients with The International Federation of Gynecology and Obstetrics (FIGO) stages II, III, and IV and timely chemotherapy is suggested if there are several weeks before the expected date of delivery. The overall prognosis of OD patients is excellent. |
| Databáze: | OpenAIRE |
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