An FMRI investigation of the cortical network underlying detection and categorization abilities in hemianopic patients

Autor: Céline Cavézian, Frédéric Andersson, Florent Caetta, Michaël Obadia, Netta Levin, Sylvie Chokron, Gaelle E. Doucet, Olivier Coubard, Julien Savatovsky, Noa Raz, F. Heran, Olivier Gout, Céline Perez, Carole Peyrin
Přispěvatelé: Laboratoire de Psychologie et NeuroCognition (LPNC), Centre National de la Recherche Scientifique (CNRS)-Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Joseph Fourier - Grenoble 1 (UJF)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry]), Laboratoire Psychologie de la Perception (LPP - UMR 8242), Université Paris Descartes - Paris 5 (UPD5)-Centre National de la Recherche Scientifique (CNRS), Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Joseph Fourier - Grenoble 1 (UJF)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Laboratoire de Psychologie et NeuroCognition ( LPNC ), Université Pierre Mendès France - Grenoble 2 ( UPMF ) -Université Joseph Fourier - Grenoble 1 ( UJF ) -Université Savoie Mont Blanc ( USMB [Université de Savoie] [Université de Chambéry] ) -Centre National de la Recherche Scientifique ( CNRS ) -Université Grenoble Alpes ( UGA ), Laboratoire Psychologie de la Perception ( LPP - UMR 8242 ), Université Paris Descartes - Paris 5 ( UPD5 ) -Centre National de la Recherche Scientifique ( CNRS )
Rok vydání: 2011
Předmět:
Adult
Male
medicine.medical_specialty
Neurology
[ SCCO.PSYC ] Cognitive science/Psychology
Audiology
Brain mapping
050105 experimental psychology
Lateralization of brain function
Functional Laterality
Brain Ischemia
Lesion
03 medical and health sciences
0302 clinical medicine
medicine
Humans
0501 psychology and cognitive sciences
Radiology
Nuclear Medicine and imaging
Vision
Ocular
Aged
Cerebral Hemorrhage
Cerebral Cortex
Brain Mapping
Radiological and Ultrasound Technology
medicine.diagnostic_test
05 social sciences
Magnetic resonance imaging
Middle Aged
Magnetic Resonance Imaging
Categorization
Case-Control Studies
[SCCO.PSYC]Cognitive science/Psychology
Visual Perception
Hemianopsia
Neurology (clinical)
Occipital Lobe
Anatomy
medicine.symptom
Visual Fields
Functional magnetic resonance imaging
Occipital lobe
Psychology
030217 neurology & neurosurgery
Cognitive psychology
Zdroj: Brain Topography: a Journal of Cerebral Function and Dynamics
Brain Topography: a Journal of Cerebral Function and Dynamics, Springer Verlag, 2013, 26 (2), pp.264-77. ⟨10.1007/s10548-012-0244-z⟩
Brain Topography
Brain Topography, Springer Verlag, 2013, 26 (2), pp.264-77. 〈10.1007/s10548-012-0244-z〉
ISSN: 1573-6792
0896-0267
DOI: 10.1007/s10548-012-0244-z⟩
Popis: International audience; The current study aims to investigate visual scene perception and its neuro-anatomical correlates for stimuli presented in the central visual field of patients with homonymous hemianopia, and thereby to assess the effect of a right or a left occipital lesion on brain reorganization. Fourteen healthy participants, three left brain damaged (LBD) patients with right homonymous hemianopia and five right brain damaged (RBD) patients with left homonymous hemianopia performed a visual detection task (i.e. "Is there an image on the screen?") and a categorization task (i.e. "Is it an image of a highway or a city?") during a block-designed functional magnetic resonance imaging recording session. Cerebral activity analyses of the posterior areas-the occipital lobe in particular-highlighted bi-hemispheric activation during the detection task but more lateralized, left occipital lobe activation during the categorization task in healthy participants. Conversely, in patients, the same network of activity was observed in both tasks. However, LBD patients showed a predominant activation in their right hemisphere (occipital lobe and posterior temporal areas) whereas RBD patients showed a more bilateral activation (in the occipital lobes). Overall, our preliminary findings suggest a specific pattern of cerebral activation depending on the task instruction in healthy participants and cerebral reorganization of the posterior areas following brain injury in hemianopic patients which could depend upon the side of the occipital lesion.
Databáze: OpenAIRE
Externí odkaz: