Sensitivity and specificity of fractal analysis to distinguish between healthy and pathologic rectal mucosa microvasculature seen during colonoscopy
| Autor: | Krzysztof Piech, Brandon Michael Henry, Krzysztof A. Tomaszewski, Marian Mrozek, Marcin Żelawski, Andrzej Gryglewski |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty animal structures Colonoscopy Gastroenterology Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Fractal Rectal mucosa Internal medicine medicine Humans natural sciences Diagnosis Computer-Assisted Prospective Studies Intestinal Mucosa Colitis Prospective cohort study medicine.diagnostic_test Rectal Neoplasms business.industry Rectum Microvascular architecture Middle Aged respiratory system medicine.disease Fractal analysis Endoscopy Fractals 030220 oncology & carcinogenesis Microvessels Female 030211 gastroenterology & hepatology Surgery business circulatory and respiratory physiology |
| Popis: | PURPOSE Conventional endoscopy is limited by human capability to recognize and to differentiate pathology. Fractal analysis of blood vessels has been used in other organs, such as the retina, but never before to supplement colonoscopy. The aim of this study was to assess whether it is possible to differentiate between healthy and pathologic rectal mucosa using fractal analysis of the mucosal microvascular architecture seen during colonoscopic examination (Supplemental Digital Content 1, http://links.lww.com/SLE/A145). METHODS A total of 300 consecutive patients, 133 females and 167 males with a mean age of 49.1 (±11.3) years, undergoing endoscopy were included in the prospective cohort study. Colonoscopy of the sigmorectal region was performed, and then analyzed with computer-assisted image fractal analysis. RESULTS Fractal analysis of mucosal vasculature allowed for differentiation between healthy and pathologic rectal mucosa, as well as different pathologies (P |
| Databáze: | OpenAIRE |
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