Lipids containing polyunsaturated fatty acids synthesized by zygomycetes grown on glycerol
| Autor: | Anna Moustogianni, Stamatia Bellou, Anna Makri, George Aggelis |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Glycerol
Bioengineering Biology Applied Microbiology and Biotechnology Biochemistry chemistry.chemical_compound Glycolipid Mortierella Biosynthesis Molecular Biology Cunninghamella echinulata Cunninghamella chemistry.chemical_classification Mucor Lipid metabolism General Medicine biology.organism_classification Lipid Metabolism Sphingolipid Lipids chemistry Fermentation Fatty Acids Unsaturated Mucorales lipids (amino acids peptides and proteins) Biotechnology Polyunsaturated fatty acid |
| Zdroj: | Applied biochemistry and biotechnology. 166(1) |
| ISSN: | 1559-0291 |
| Popis: | Several strains of Zygomycetes cultivated on glycerol produced mycelia rich in lipids containing higher amounts of neutral lipids (NL) than glycolipids plus sphingolipids and phospholipids (P), while biosynthesis of P in Mortierella ramanniana, Mucor sp., and Cunninghamella echinulata occurred though NL accumulation process was in progress. Polyunsaturated fatty acids (PUFA) concentration gradually decreased in all lipid fractions of M. ramanniana during growth. In contrast, in C. echinulata concentration of both linoleic and γ-linolenic acids increased with time, especially in P. Taking for granted that the main function of PUFA is associated to their participation in mycelial membranes, we could suppose that biosynthesis of these fatty acids is associated to mycelial growth. However, this is accurate only for some Zygomycetes, e.g., M. ramanniana. On the contrary, PUFA biosynthesis in C. echinulata persists after growth cessation, suggesting that in this species biosynthetic ability is not a strictly growth-associated process. Phosphatidyl-inositol and phosphatidyl-choline were the major P classes in C. echinulata and M. ramanniana, respectively. In M. ramanniana, a decrease of PUFA concentration was noticed even when mycelia were incubated in low temperature (conditions that normally favor PUFA biosynthesis), indicating that PUFA biosynthesis in this fungus is associated to primary metabolism. |
| Databáze: | OpenAIRE |
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