EPIC-Heart: The cardiovascular component of a prospective study of nutritional, lifestyle and biological factors in 520,000 middle-aged participants from 10 European countries

Autor: Kay-Tee Khaw, Göran Hallmans, Concepción Moreno Iribas, Nadia Slimani, María José Sánchez Pérez, Dimitrios Trichopoulos, Anne Tjønneland, Agnès Fournier, Françoise Clavel-Chapelon, Heiner Boeing, Edith J. M. Feskens, Rosario Tumino, Jakob Linseisen, Kim Overvad, Søren Paaske Johnsen, Tobias Pischon, Yvonne T. van der Schouw, Majken K. Jensen, Carlos Alberto Gonzalez Svatetz, Giovanna Masala, Sabina Sieri, Nicholas J. Wareham, Cornelia Weikert, Vassiliki Benetou, Elio Riboli, Simon G. Thompson, Rodolfo Saracci, Merethe Kumle, Anja Olsen, W. M. Monique Verschuren, Diederick E. Grobbee, Sheila Bingham, Antonia Trichopoulou, Nerea Larrañaga, Pietro Ferrari, Salvatore Panico, Guri Skeie, Amalia Mattiello, Timothy J. Key, Andrew W. Roddam, José Ramón Quirós, Patrik Wennberg, Göran Berglund, John Danesh, Carlotta Sacerdote, Marianne Canonico, Eiliv Lund, Rudolf Kaaks, Carmen Navarro Sánchez, Olle Melander, H. Bas Bueno-de-Mesquita, Teresa Norat
Přispěvatelé: Department of Public Health & Primary Care, University of Cambridge [UK] (CAM), Centre International de Recherche contre le Cancer - International Agency for Research on Cancer (CIRC - IARC), Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), Department of Clinical Sciences, Lund University [Lund]-Malmö University Hospital, Division of Human Nutrition, Wageningen University and Research [Wageningen] (WUR), Department of Clinical Epidemiology, Aarhus University Hospital, Department of Clinical and Experimental Medicine, University of Naples Federico II = Università degli studi di Napoli Federico II, Plasmon Nano-optics, Institut de Ciencies Fotoniques [Castelldefels] (ICFO), Nutrition, hormones et cancer: épidémiologie et prévention (E3N), Epidémiologie, sciences sociales, santé publique (IFR 69), Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris-Sud - Paris 11 (UP11)-École des hautes études en sciences sociales (EHESS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris-Sud - Paris 11 (UP11)-École des hautes études en sciences sociales (EHESS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), INSERM UNIT 780: Epidemiology and biostatistics, Paul-Brousse Hospital, Division of Cancer Epidemiology, German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Institute of Cancer Epidemiology, Danish Cancer Society, Centre for Ice and Climate [Copenhagen], Niels Bohr Institute [Copenhagen] (NBI), Faculty of Science [Copenhagen], University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH)-Faculty of Science [Copenhagen], University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH), Public Health and Health Planning Directorate, Gobierno del Principado de Asturias-Consejeria de Salud y Servicios Sanitarios, Catalan Institute of Oncology, Matériaux, ingénierie et science [Villeurbanne] (MATEIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS), Public Health Department of Gipuzkoa, Laboratoire de Chimie de la Matière Condensée de Paris (LCMCP), Université Pierre et Marie Curie - Paris 6 (UPMC)-Collège de France (CdF (institution))-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Public Health Institute of Navarra, MRC Centrer for Nutritional Epidemiology and Cancer Prevention and Survival, Clinical Gerontology Unit, MRC epidemiology Unit, Addenbrooke's Hospital, Cancer Epidemiology Unit, University of Oxford, Cancer Research UK Epidemiology Unit, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School [Athens], WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Molecular and Nutritional Epidemiology Unit (ISPO), Cancer Research and Prevention Institute, Nutritional Epidemiology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Cancer Registry and Histopathology Unit, Civile - M.P.Arezzo Hospital, Center for Cancer Prevention, CPO-Piemonte, National Institute for Public Health and the Environment [Bilthoven] (RIVM), Julius Center for Health Sciences and Primary Care, University Medical Center [Utrecht], Department of Medecine, Skellefteå Hospital, Skellefteå Hospital, Skellefteå, Suède, Institute of Community Medicine University of Tromsø, Centro Ricerche Produzioni Animali (CRPA), Dietary Exposure Assessment Grp, Int Agcy Res Canc, School of Public Health, Imperial College London, Department of Epidemiology and Biostatistics, SZTAJNBOK, Pascale, IRCCS Istituto Nazionale dei Tumori [Milano], Università degli studi di Napoli Federico II, Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris-Sud - Paris 11 (UP11)-École des hautes études en sciences sociales (EHESS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris-Sud - Paris 11 (UP11)-École des hautes études en sciences sociales (EHESS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Gustave Roussy (IGR)-Université Paris-Sud - Paris 11 (UP11), University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU)-Faculty of Science [Copenhagen], University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Collège de France (CdF (institution))-Institut de Chimie du CNRS (INC), University of Oxford [Oxford], University Medical Centre Utrecht
Rok vydání: 2007
Předmět:
Male
Gerontology
coronary-artery-disease
Nutrition and Disease
Epidemiology
population
030204 cardiovascular system & hematology
Coronary artery disease
0302 clinical medicine
Voeding en Ziekte
Surveys and Questionnaires
Prospective Studies
030212 general & internal medicine
Prospective cohort study
risk
education.field_of_study
Anthropometry
Middle Aged
3. Good health
European Prospective Investigation into Cancer and Nutrition
Europe
Cardiovascular Diseases
fat distribution
Female
women
prospective study
Adult
medicine.medical_specialty
Population
Nutritional Status
03 medical and health sciences
medicine
Humans
cancer
plasma-levels
ddc:610
education
Life Style
dietary assessment methods
VLAG
Aged
Global Nutrition
Wereldvoeding
business.industry
Public health
norfolk cohort
medicine.disease
Middle age
[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie
high blood-pressure
EPIC Heart
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
diet
business
study protocol
Zdroj: European Journal of Epidemiology 22 (2007) 2
European Journal of Epidemiology
European Journal of Epidemiology, 2006, 22 (2), pp.129-41
European Journal of Epidemiology, 22(2), 129-141
European Journal of Epidemiology, Springer Verlag, 2006, 22 (2), pp.129-41
ISSN: 1573-7284
0393-2990
Popis: International audience; EPIC-Heart is the cardiovascular component of the European Prospective Investigation into Cancer and Nutrition (EPIC), a multi-centre prospective cohort study investigating the relationship between nutrition and major chronic disease outcomes. Its objective is to advance understanding about the separate and combined influences of lifestyle (especially dietary), environmental, metabolic and genetic factors in the development of cardiovascular diseases by making best possible use of the unusually informative database and biological samples in EPIC. Between 1992 and 2000, 519,978 participants (366,521 women and 153,457 men, mostly aged 35-70 years) in 23 centres in 10 European countries commenced follow-up for cause- specific mortality, cancer incidence and major cardiovascular morbidity. Dietary information was collected with quantitative questionnaires or semi-quantitative food frequency questionnaires, including a 24-h dietary recall sub-study to help calibrate the dietary measurements. Information was collected on physical activity, tobacco smoking, alcohol consumption, occupational history, socio-economic status, and history of previous illnesses. Anthropometric measurements and blood pressure recordings were made in the majority of participants. Blood samples were taken from 385,747 individuals, from which plasma, serum, red cells, and buffy coat fractions were separated and aliquoted for long-term storage. By 2004, an estimated 10,000 incident fatal and non-fatal coronary and stroke events had been recorded. The first cycle of EPIC-Heart analyses will assess associations of coronary mortality with several prominent dietary hypotheses and with established cardiovascular risk factors. Subsequent analyses will extend this approach to non-fatal cardiovascular outcomes and to further dietary, biochemical and genetic factors.
Databáze: OpenAIRE
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