Pre-Pregnancy Body Mass Index and Weight Gain During Pregnancy: Relations with Gestational Diabetes and Hypertension, and Birth Outcomes

Autor: Monique Kaminski, Anne Forhan, Olivier Thiebaugeorges, Marie-Aline Charles, Michel Schweitzer, Bernard Foliguet, Guillaume Magnin, Valérie Goua, Barbara Heude
Přispěvatelé: Centre de recherche en épidémiologie et santé des populations ( CESP ), Université de Versailles Saint-Quentin-en-Yvelines ( UVSQ ) -Université Paris-Sud - Paris 11 ( UP11 ) -Assistance publique - Hôpitaux de Paris (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Service de Foetopathologie et placentologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy ( CHRU Nancy ), Service de gynécologie et obstétrique [Poitiers], Université de Poitiers-Centre hospitalier universitaire de Poitiers ( CHU Poitiers ), Recherche Epidémiologique en Santé Périnatale et Santé des Femmes et des Enfants ( UMR_S 953 ), Université Paris-Sud - Paris 11 ( UP11 ) -Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), We acknowledge all the funding sources for the EDEN study: Fondation pour la Recherche Médicale (FRM), French Ministry of Research: IFR and Cohort program, INSERM Nutrition Research Program, French Ministry of Health Perinatality Program, French Agency for Environment Security (AFFSET), French National Institute for Population Health Surveillance (INVS), Paris-Sud University, French National Institute for Health Education (INPES), Nestlé, Mutuelle Générale de l'Education Nationale (MGEN), French speaking association for the study of diabetes and metabolism (Alfediam), National Agency for Research (ANR non thematic program), National Institute for Research in Public Health (IRESP: TGIR cohorte santé 2008 program), EDEN Mother-Child Cohort Study group
Rok vydání: 2011
Předmět:
Epidemiology
Weight Gain
Body Mass Index
Fetal Macrosomia
0302 clinical medicine
Pregnancy
Risk Factors
Birth Weight
MESH : Female
030212 general & internal medicine
2. Zero hunger
MESH : Pregnancy Outcome
030219 obstetrics & reproductive medicine
Obstetrics
Pregnancy Outcome
Obstetrics and Gynecology
Gestational age
MESH : Weight Gain
MESH : Infant
[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologie
MESH : Adult
MESH : Maternal Age
MESH : Risk Factors
3. Good health
Gestational diabetes
MESH : Hypertension
Pregnancy-Induced
Gestation
MESH : Obesity
Female
gestational diabetes
medicine.symptom
Maternal Age
Adult
medicine.medical_specialty
hypertension
Birth weight
Gestational Age
Article
03 medical and health sciences
medicine
Fetal macrosomia
Humans
Obesity
business.industry
MESH : Humans
Public Health
Environmental and Occupational Health
Infant
MESH : Birth Weight
Hypertension
Pregnancy-Induced
medicine.disease
MESH : Pregnancy
MESH : Body Mass Index
Diabetes
Gestational
MESH : Fetal Macrosomia
Pediatrics
Perinatology and Child Health
MESH : Diabetes
Gestational
business
Body mass index
Weight gain
MESH : Gestational Age
Zdroj: Maternal and Child Health Journal
Maternal and Child Health Journal, Springer Verlag, 2012, 16 (2), pp.355-63. 〈10.1007/s10995-011-0741-9〉
ISSN: 1573-6628
1092-7875
DOI: 10.1007/s10995-011-0741-9
Popis: International audience; To study the relationship between pre-pregnancy body mass index (BMI) and weight gain during pregnancy with pregnancy and birth outcomes, with a focus on gestational diabetes and hypertension and their role in the association with fetal growth. We studied 1,884 mothers and offspring from the Eden mother-child cohort. Weight before pregnancy (W1) and weight after delivery (W2) were collected and we calculated BMI and net gestational weight gain (netGWG = (W2 - W1)/(weeks of gestation)). Gestational diabetes, hypertension gestational age and birth weight were collected. We used multivariate linear or logistic models to study the association between BMI, netGWG and pregnancy and birth outcomes, adjusting for center, maternal age and height, parity and average number of cigarettes smoked per day during pregnancy. High BMI was more strongly related to the risk of giving birth to a large-for-gestational-age (LGA) baby than high netGWG (odds ratio OR [95% CI] of 3.23 [1.86-5.60] and 1.61 [0.91-2.85], respectively). However, after excluding mothers with gestational diabetes or hypertension the ORs for LGA, respectively weakened (OR 2.57 [1.29-5.13]) for obese women and strengthened for high netGWG (OR 2.08 [1.14-3.80]). Low in comparison to normal netGWG had an OR of 2.18 [1.20-3.99] for pre-term birth, which became stronger after accounting for blood pressure and glucose disorders (OR 2.70 [1.37-5.34]). Higher net gestational weight gain was significantly associated with an increased risk of LGA only after accounting for blood pressure and glucose disorders. High gestational weight gain should not be neglected in regard to risk of LGA in women without apparent risk factors.
Databáze: OpenAIRE
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