Increased risk of preterm delivery and pre-eclampsia in women with polycystic ovary syndrome and hyperandrogenaemia
| Autor: | J Grinsted, Severin Olesen Larsen, Paula L. Hedley, Klara Vinsand Naver, Lisbeth Nilas, Michael Christiansen, Finn Stener Jørgensen |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
medicine.medical_specialty Population Body Mass Index Cohort Studies Pre-Eclampsia Pregnancy medicine Humans education Gynecology education.field_of_study Eclampsia Obstetrics business.industry Infant Newborn Obstetrics and Gynecology Odds ratio medicine.disease Polycystic ovary female genital diseases and pregnancy complications Parity Case-Control Studies Infant Small for Gestational Age Cohort Premature Birth Regression Analysis Small for gestational age Female Hyperandrogenism business Body mass index Maternal Age Polycystic Ovary Syndrome Cohort study |
| Zdroj: | BJOG: An International Journal of Obstetrics & Gynaecology. 121:575-581 |
| ISSN: | 1470-0328 |
| DOI: | 10.1111/1471-0528.12558 |
| Popis: | Objective To study the risk of adverse pregnancy outcomes in women with polycystic ovary syndrome (PCOS), and to examine the role of hyperandrogenaemia. Design Cohort study. Setting Singleton pregnancies in women with PCOS identified at a private fertility clinic during 1997–2010 and a background population including all singleton deliveries at Hvidovre Hospital, Denmark, in 2005. Population A cohort of 459 women with PCOS and a background population of 5409 women. Methods Obstetric outcomes were extracted from national Danish registries and odds ratios (ORs) were calculated by multiple logistic regression analysis, adjusting for age, parity, and body mass index. Main outcome measures Risk of pre-eclampsia, preterm delivery, and small for gestational age offspring in the entire PCOS population and in a subsample with hyperandrogenaemia. Results Women with PCOS had an increased risk of preterm delivery |
| Databáze: | OpenAIRE |
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