FAMILIAL 78XX MALE PSEUDOHERMAPHRODITISM IN THREE DOGS

Autor:	R. A. Mcfeely, D. F. Kelly, W. C. D. Hare
Rok vydání:	1974
Předmět:	Male Embryology Uterus Disorders of Sex Development Obstetrics and Gynecology Chromosome Physiology Horse Cell Biology Biology Dogs Endocrinology Reproductive Medicine External genitalia Male pseudohermaphroditism Animals Female Sex organ Dog Diseases Genitalia Gonads Sex Chromosome Aberrations
Zdroj:	Reproduction. 36:207-210
ISSN:	1741-7899 1470-1626
DOI:	10.1530/jrf.0.0360207
Popis:	Abnormal mammalian gonadal and, consequently, genital differentiation usually occurs with heteroploidy and other abnormalities of the sex chromosomes, but can also occur when the sex chromosome constitution appears to be normal. One expression of the latter situation is in cases of male pseudohermaphroditism with two X, but apparently no Y, sex chromosomes. There have been several reports of this in man (see de la Chapelle, 1972), pig (see Breeuwsma, 1970), goat (see Hamerton, Dickson, Pollard, Grieves & Short, 1969) and horse (Bornstein, 1967; Generke & Coubrough, 1970), but only one in the dog (Edols & Allan, 1968). This paper describes three more cases in closely related dogs with similar anatomical abnormalities. The propositi were three English cocker spaniels, two (A and B) were littermates, and the third (C) was a sib (Text-fig. 1). They were first seen at 2 months of age showing almost identical abnormalities of the external genitalia
Databáze:	OpenAIRE
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