Effects of arginine vasotocin on REM sleep in narcoleptics and in symptomatic hypersomniacs

Autor: M Tudosie, Földes A, Popoviciu L, Pavel S, Corfariu O
Rok vydání: 1982
Předmět:
Zdroj: Electroencephalography and clinical neurophysiology. 53(3)
ISSN: 0013-4694
Popis: Arginine vasotocin (AVT), in doses of 1.5 microgram, administered intranasally to two narcoleptics (a male aged 42 years and a female aged 35 years), as well as to 5 symptomatic hypersomniacs (3 females and 2 males), aged 25-57 years, induced very rapidly in most instances in sleep with REM periods at onset and markedly increased in amount of REM sleep during a fixed period of 180 min of sleep recording. After AVT administration there was a significant shortening of the time of occurrence of the first REM sleep period both in narcoleptics (t test = 0.05 greater than P greater than 0.025) and in symptomatic hypersomniacs (t test = 0.02 greater than P greater than 0.01).
Databáze: OpenAIRE