The effect of two skin cleansing systems on moderate xerotic eczema
| Autor: | Zoe Diana Draelos, Paula Hartwig, Gayle Y. Rains, Keith D. Ertel |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Adult
medicine.medical_specialty Triamcinolone acetonide Erythema Adolescent Petrolatum medicine.drug_class Xerotic eczema Administration Topical Eczema Fluocinonide Dermatology Soaps Triamcinolone Acetonide Desquamation Cleanser Adrenal Cortex Hormones Medicine Potency Humans Aged business.industry Middle Aged medicine.disease Skin Care Patient Satisfaction Polyethylene Corticosteroid medicine.symptom business medicine.drug |
| Zdroj: | Journal of the American Academy of Dermatology. 50(6) |
| ISSN: | 0190-9622 |
| Popis: | Background Moderate xerotic eczema, characterized by stratum corneum desquamation, erythema, and pruritis is a common condition that can be induced or worsened by skin cleansing. Traditional dermatologic therapy includes the use of emollients, medium or high potency topical corticosteroids, and a change in bathing habits. Objective To investigate the effect of two cleansing systems: a synthetic detergent bar soap applied with a cotton washcloth and a petrolatum-delivering body wash applied with a polyethylene puff as part of a topical treatment approach to moderate xerotic eczema. Method Sixty patients with moderate xerotic eczema were enrolled in a 4-week investigator-blinded study. Half were randomly treated with a strong topical corticosteroid cream (0.05% fluocinonide) and a traditional cleansing system consisting of a synthetic detergent bar soap applied with a washcloth. The remaining patients were treated with a weaker, medium strength topical corticosteroid cream (0.1% triamcinolone acetonide) and a novel cleansing system consisting of a petrolatum-delivering body wash applied with a polyethylene puff. Dermatologist investigator evaluations and patient self-assessments were conducted at baseline, 2 weeks, and 4 weeks. Results Patients using the novel petrolatum-delivering body wash and polyethylene puff cleansing system and the lower potency corticosteroid cream demonstrated significantly greater clinical improvement than those patients using the traditional cleansing system of a synthetic detergent beauty bar and washcloth system and the higher potency corticosteroid cream after both 2 and 4 weeks of treatment. Conclusion The cleansing system of a petrolatum-delivering body wash delivered by a polyethylene puff may be useful as a cleanser for patients with moderate xerotic eczema. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect