Comparing Glaucomatous Disc Change Using Stereo Disc Viewing and the MatchedFlicker® Software Program in Ophthalmologists in Training

Autor: Jamie L. Schaefer, Alissa M. Meyer, Anthony J. Leoncavallo, Baiming Zou, Jonathan J. Shuster, Mark B. Sherwood, Zachary L. Lukowski, Gina M. Martorana, Anthony Greer
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Diagnostic Imaging
Retinal Ganglion Cells
medicine.medical_specialty
genetic structures
Optic Disk
Optic disk
Glaucoma
Ocular hypertension
Stereoscopy
Diagnostic Techniques
Ophthalmological
Sensitivity and Specificity
Article
law.invention
03 medical and health sciences
0302 clinical medicine
Nerve Fibers
law
Predictive Value of Tests
Ophthalmology
Optic Nerve Diseases
Medical imaging
Photography
Medicine
Humans
False Positive Reactions
Prospective Studies
business.industry
Flicker
Teaching
Internship and Residency
Reproducibility of Results
Gold standard (test)
medicine.disease
eye diseases
medicine.anatomical_structure
Education
Medical
Graduate
030221 ophthalmology & optometry
Disease Progression
sense organs
business
030217 neurology & neurosurgery
Glaucoma
Open-Angle
Software
Optic disc
Popis: Purpose To compare the accuracy and speed of using the computerized MatchedFlicker software program (EyeIC Inc, Narberth, Pennsylvania, USA) to evaluate glaucomatous optic disc change against the traditional gold standard of manually examining stereoscopic disc photographs. Design A prospective evaluation of diagnostic technology. Methods Two resident ophthalmologists and 1 glaucoma fellow at the University of Florida independently evaluated 140 image pairs from 100 glaucomatous/ocular hypertensive patient eyes using a handheld stereo viewer and the MatchedFlicker program. Fifty had progression to glaucoma as determined by the Ocular Hypertension Treatment Study (OHTS) Optic Disc Reading Group and the OHTS Endpoint Committee in the OHTS, and 50 more had photographs taken a few minutes apart, which were negative controls with no progression. Twenty photograph pairs from each group were duplicated to determine reviewer variability. Photographs were examined in alternating blocks of 70 photograph pairs for each method, with the starting viewing method randomized. Reviewer accuracy and time to review for each method were measured. Results Using the handheld stereo viewer, the reviewers correctly identified progression or nonprogression in 76.0% of the slide pairs. Using the MatchedFlicker software, 87.6% were correctly identified ( P = .011). Evaluator speed averaged 34.1 seconds per image pair with the stereo viewer vs 24.9 seconds with the MatchedFlicker program ( P = .044). Overall, Flicker was significantly more specific but less sensitive than stereo slides. Trainees appeared more reluctant to identify glaucoma progression from slides than from Flicker. For the 2 less experienced trainees Flicker was significantly more accurate. Conclusion The MatchedFlicker software had a greater accuracy and was quicker to perform than using a handheld stereoscopic viewer.
Databáze: OpenAIRE
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