ESTRO consensus guideline on target volume delineation for elective radiation therapy of early stage breast cancer

Autor: Meritxell Arenas, Albert Biete Sola, Caroline Weltens, Angel Montero, Jean-Philippe Pignol, Vincent Remouchamps, John Yarnold, Neil Kopek, Liesbeth J. Boersma, Philip Poortmans, Marianne C. Aznar, Youlia M. Kirova, Dorota Gabrys, Carine Kirkove, Birgitte Vrou Offersen, Mechthild Krause, K. Verhoeven, S. Hol, Dan Lundstedt, Tanja Marinko
Přispěvatelé: Radiotherapie, RS: GROW - Oncology, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Hematology, Radiotherapy
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Radiotherapy and Oncology, 114(1), 3-10. Elsevier Ireland Ltd
Radiotherapy and Oncology 114(2015)1, 3-10
Radiotherapy and Oncology, 114, 1, pp. 3-10
Offersen, B V, Boersma, L J, Kirkove, C, Hol, S, Aznar, M C, Biete Sola, A, Kirova, Y M, Pignol, J-P, Remouchamps, V, Verhoeven, K, Weltens, C, Arenas, M, Gabrys, D, Kopek, N, Krause, M, Lundstedt, D, Marinko, T, Montero, A, Yarnold, J & Poortmans, P 2015, ' ESTRO consensus guideline on target volume delineation for elective radiation therapy of early stage breast cancer ', Radiotherapy & Oncology, vol. 114, no. 1, pp. 3-10 . https://doi.org/10.1016/j.radonc.2014.11.030
Radiotherapy and Oncology, 114, 3-10
ISSN: 0167-8140
DOI: 10.1016/j.radonc.2014.11.030
Popis: Background and purpose: Delineation of clinical target volumes (CTVs) is a weak link in radiation therapy (RT), and large inter-observer variation is seen in breast cancer patients. Several guidelines have been proposed, but most result in larger CTVs than based on conventional simulator-based RT. The aim was to develop a delineation guideline obtained by consensus between a broad European group of radiation oncologists. Material and methods: During ESTRO teaching courses on breast cancer, teachers sought consensus on delineation of CTV through dialogue based on cases. One teacher delineated CTV on CT scans of 2 patients, followed by discussion and adaptation of the delineation. The consensus established between teachers was sent to other teams working in the same field, both locally and on a national level, for their input. This was followed by developing a broad consensus based on discussions. Results: Borders of the CTV encompassing a 5 mm margin around the large veins, running through the regional lymph node levels were agreed, and for the breast/thoracic wall other vessels were pointed out to guide delineation, with comments on margins for patients with advanced breast cancer. Conclusion: The ESTRO consensus on CTV for elective RT of breast cancer, endorsed by a broad base of the radiation oncology community, is presented to improve consistency. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
Databáze: OpenAIRE