Cerebral venous sinus thrombosis associated with COVID-19: a case series and literature review
Autor: | Farzad Mardi, Ashkan Mowla, Shima Shahjouei, Mohammad Saied Salehi, Nima Fadakar, Mostafa Almasi-Dooghaee, Mahmoud Reza Azarpazhooh, Afshin Borhani-Haghighi, Maryam Poursadeghfard, Abbas Rahimi-Jaberi, Razieh Foroughi, Ramin Zand, Seyedeh Shaghayegh Zafarmand, Vahid Reza Ostovan, Anahid Safari, Manouchehr Esmaili, Etrat Hooshmandi, Ali Akbar Bidaki, Maryam Owjfard, Mahtab Rostami, Hoda Marbooti, Farzane Farzadfard, Mahnaz Bayat, Zahra Behzadi |
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Rok vydání: | 2021 |
Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Neurology Coronavirus disease 2019 (COVID-19) viruses Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Sinus Thrombosis Intracranial 03 medical and health sciences 0302 clinical medicine medicine Humans 030212 general & internal medicine Cerebral venous sinus thrombosis skin and connective tissue diseases Pandemics Stroke Sinus thrombosis Neuroradiology Original Communication SARS-CoV-2 business.industry Research Mortality rate fungi COVID-19 Infection diagnosis Middle Aged medicine.disease Intracranial respiratory tract diseases Coronavirus body regions Female Neurology (clinical) business 030217 neurology & neurosurgery |
Zdroj: | Journal of Neurology |
ISSN: | 1432-1459 0340-5354 |
Popis: | Background: Since the COVID-19 pandemic, several cases of cerebral venous sinus thrombosis (CVST) have been reported in SARS-CoV-2 infected individuals. This study provides a series of patients with CVST and SARS-CoV-2 infection.Methods: Consecutive patients with documented SARS-CoV-2 infection, as well as clinical and radiological characteristics of CVST, were reported from three teaching hospitals in the South West, North West, and the center of Iran from June to July 2020. We also searched the abstract archives until the end of August 2020 and gathered 28 reported cases. The diagnostic criteria for SARS-CoV-2 infection were determined according to SARS-CoV-2 detection in oropharyngeal or nasopharyngeal samples in clinically suspected patients. Demographics, main COVID-19 symptoms, confirmatory tests for SARS-CoV-2 infection diagnosis, the interval between the diagnosis of SARS-CoV-2 infection and CVST, clinical and radiological features of CVST, therapeutic strategies, CVST outcomes, rate of hemorrhagic transformation, and mortality rate were investigated.Results: Six patients (aged 31 to 62 years old) with confirmed CVST and SARS-CoV-2 infection were admitted to our centers. Four patients had no respiratory symptoms of SARS-CoV-2 infection. Five out of six patients developed the clinical manifestations of CVST and SARS-CoV-2 infection simultaneously. Three patients had known predisposing factors for CVST. Despite receiving CVST and SARS-CoV-2 infection treatments, four out of six patients passed away.Conclusions: The role of SARS-CoV-2 as a “cause” versus an “additive contributor” remains to be elucidated. Practitioners should be aware of the possibility of CVST in SARS-CoV-2 infection. |
Databáze: | OpenAIRE |
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