Mid-term assessment of cardiac autonomic functions in children with transposition of the great arteries after arterial switch operation
| Autor: | Vedide Tavli, Faik Fevzi Okur, Rahmi Özdemir, Utku Karaarslan, Emin Alp Alayunt, Barış Güven, Önder Doksöz, Timur Meşe, Yilmaz Yozgat, Taliha Öner |
|---|---|
| Přispěvatelé: | YOZGAT, YILMAZ |
| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Heart disease Transposition of Great Vessels Autonomic Nervous System Cohort Studies Transposition (music) Electrocardiography Heart Rate Internal medicine Humans Medicine Heart rate variability Postoperative Period Vagal tone Child Balance (ability) business.industry medicine.disease Great arteries Case-Control Studies Electrocardiography Ambulatory Mann–Whitney U test Cardiology Female Cardiology and Cardiovascular Medicine business circulatory and respiratory physiology Cohort study |
| Zdroj: | Anadolu Kardiyoloji Dergisi/The Anatolian Journal of Cardiology. 14:735-740 |
| ISSN: | 1308-0032 1302-8723 |
| DOI: | 10.5152/akd.2014.5124 |
| Popis: | OBJECTIVE It has been documented that impaired heart rate variability (HRV) is related to life threatening arrhythmias in children with surgically repaired congenital heart disease. We aimed to analyze the balance of the cardiac autonomic functions by assessing HRV in children with arterial switch operation (ASO). METHODS In this observational cohort study, HRV analysis using 24-h Holter electrocardiography recordings was examined in 22 patients (mean age: 59.5±38.7 months, 18 male, 4 female) who had undergone ASO during the newborn period and 22 healthy children (mean age: 65.1±39.4 months, 18 male, 4 female). After Kolmogorov-Smirnov testing for normality, Student t-test and Mann-Whitney U test were used when appropriate. Chi-square was used for categorical data. RESULTS In 24-h HRV analysis showed that SDANN and VLF were significantly higher in patient group. Awake SDNN, rMSSD, pNN50, TP and VLF levels of patient group were significantly higher than those of control subjects. Awake LF/HF ratio in patient group was significantly higher than their counterpart in asleep group. In the patient group, awake rMSSD, pNN50, TP, LF and HF were significantly lower than their counterpart in the asleep group. CONCLUSION Children with transposition of the great arteries (TGA) following ASO have not decreased levels of time and frequency HRV parameters in the mid-term follow-up period. All HRV parameters reflecting vagal tone were increased in the patient group. It is suggested that vagal tone is more predominant than sympathetic tone for children with ASO. |
| Databáze: | OpenAIRE |
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