Effect of chelation therapy on arrhythmogenic and basal ECG parameters of lead exposed workers
| Autor: | Ahmet Göktuğ Ertem, Mehmet Akif Erdöl, Sefa Ünal, Çağrı Yayla, Meşide Gündüzöz, Murat Karakurt, Ahmet Akdi, Kursat Akbuga, Mustafa Bilal Ozbay, Emre Aruğaslan, Ozcan Ozeke, Mustafa Karanfil |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Health Toxicology and Mutagenesis 010501 environmental sciences Toxicology 01 natural sciences 03 medical and health sciences Basal (phylogenetics) Electrocardiography 0302 clinical medicine Internal medicine Medicine Humans Chelation therapy Lead (electronics) Stroke 0105 earth and related environmental sciences General Environmental Science business.industry Public Health Environmental and Occupational Health Arrhythmias Cardiac medicine.disease 030210 environmental & occupational health Chelation Therapy Lead Lead exposure Cardiology Etiology business |
| Zdroj: | Archives of environmentaloccupational health. 77(5) |
| ISSN: | 2154-4700 |
| Popis: | Lead exposure has etiological role on cardiovascular system diseases as hypertension, atherosclerosis, stroke, and arrhythmic events. In this study, we aimed to compare the basal and arrhythmogenic ECG parameters of lead exposed workers before and after chelation therapy and to evaluate the effect of acute change of blood lead levels on ECG. Fourty consecutive occupationally lead exposed workers were enrolled, demographic, blood, echocardiographic, and electrocardiographic data's were analyzed before and after chelation therapy. Pmax, P min, P Wave Dispersion, and QT Dispersion values which are arrhythmia predictors were significantly lower after chelation therapy compared to values before chelation therapy. Lead exposed workers are under the risk of ventricular and atrial arrythmias and chelation treatment has a positive effect on these parameters. |
| Databáze: | OpenAIRE |
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