The Search for Submammalian Gastrins: The Identification of Amphibian Gastrin
| Autor: | H. W. Colvin, R. G. Gibson, A.A. Mihas, Basil I. Hirschowitz |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Amphibian
medicine.medical_specialty Duodenum Radioimmunoassay digestive system General Biochemistry Genetics and Molecular Biology Amphibians Necturus Internal medicine biology.animal Gastrins Pyloric Antrum medicine Animals Pancreas Antrum Gastrin Rana catesbeiana biology Rana pipiens digestive oral and skin physiology biology.organism_classification Molecular Weight medicine.anatomical_structure Endocrinology Tissue extracts Digestive System hormones hormone substitutes and hormone antagonists |
| Zdroj: | Experimental Biology and Medicine. 153:284-288 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-153-39529 |
| Popis: | SummaryExtracts of the digestive tracts of three amphibian species were examined by radioimmunoassay for gastrin-like materials. Gastrin was detected in all three species of amphibia examined. In R. cates-beiana and R. pipiens the largest tissue concentrations of gastrin were found in the antrum, followed by the duodenum and pancreas, respectively, in order of decreasing gastrin content. In the urodele Necturus the duodenum contained the highest tissue content of gastrin followed by the antrum and then the pancreas.Molecular heterogeneity of gastrin was found in the sera of R. catesbeiana and in tissue extracts of R. catesbeiana and Necturus. |
| Databáze: | OpenAIRE |
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