Evidence for Associated Cutaneous Microangiopathy in Diabetic Patients With Neuropathic Foot Ulceration

Autor: Nathalie Chabbert-Buffet, Claude LeDevehat, Nathalie Abdoucheli-Baudot, Michel Vayssairat, Laurent Tribout, Taraneh Khodabandhelou, Jean Pierre Gaitz, Eric Allaire
Rok vydání: 2003
Předmět:
Zdroj: Diabetes Care. 26:960-961
ISSN: 1935-5548
0149-5992
DOI: 10.2337/diacare.26.3.960
Popis: Diabetes complicated by diabetic neuropathy is a risk factor initiating chronic foot ulceration, which may lead to amputation (1). We postulated that a form of functional cutaneous microangiopathy is associated with diabetic neuropathy, and we assessed the cutaneous vasoreactivity reserve (CVR) using laser-Doppler flowmetry. We investigated 42 patients with type 2 diabetes but without cutaneous foot ischemia. They were divided into two groups, respectively comprising 30 patients with no current or previous foot ulceration and 12 with diabetic neuropathy and foot ulceration. A total of 17 healthy subjects served as the control group. A laser-Doppler probe was placed …
Databáze: OpenAIRE