Effect of peer health workers on AIDS care in Rakai, Uganda: a cluster-randomized trial
Autor: | Arnold H. Packer, Gertrude Nakigozi, Thomas C. Quinn, Robert C. Bollinger, Steven J. Reynolds, Joseph Kagaayi, David Serwadda, Victor Ssempijja, Ronald H. Gray, Larry W. Chang |
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Jazyk: | angličtina |
Rok vydání: | 2010 |
Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Adolescent Anti-HIV Agents Health Personnel Public Health and Epidemiology/Infectious Diseases lcsh:Medicine Peer Group law.invention 03 medical and health sciences Young Adult 0302 clinical medicine Pharmacotherapy Randomized controlled trial Acquired immunodeficiency syndrome (AIDS) law Medicine Cluster Analysis Humans Uganda 030212 general & internal medicine Cluster randomised controlled trial Young adult lcsh:Science Aged Acquired Immunodeficiency Syndrome 030505 public health Multidisciplinary Intention-to-treat analysis business.industry lcsh:R Public Health and Epidemiology/Global Health Middle Aged Viral Load Infectious Diseases/HIV Infection and AIDS medicine.disease Confidence interval 3. Good health Relative risk Patient Compliance Female lcsh:Q 0305 other medical science business Research Article |
Zdroj: | PLoS ONE, Vol 5, Iss 6, p e10923 (2010) PLoS ONE |
ISSN: | 1932-6203 |
Popis: | Background Human resource limitations are a challenge to the delivery of antiretroviral therapy (ART) in low-resource settings. We conducted a cluster randomized trial to assess the effect of community-based peer health workers (PHW) on AIDS care of adults in Rakai, Uganda. Methodology/Principal Findings 15 AIDS clinics were randomized 2∶1 to receive the PHW intervention (n = 10) or control (n = 5). PHW tasks included clinic and home-based provision of counseling, clinical, adherence to ART, and social support. Primary outcomes were adherence and cumulative risk of virologic failure (>400 copies/mL). Secondary outcomes were virologic failure at each 24 week time point up to 192 weeks of ART. Analysis was by intention to treat. From May 2006 to July 2008, 1336 patients were followed. 444 (33%) of these patients were already on ART at the start of the study. No significant differences were found in lack of adherence ( |
Databáze: | OpenAIRE |
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