Cell population data: Could a routine hematology analyzer aid in the differential diagnosis of COVID‐19?
| Autor: | Iva Lukić, Maja Lukić, Tina Brencic, Monika Kovačić, Vatroslav Šerić, Ivana Lapić, Lorena Honović, Dunja Rogić |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty 2019-20 coronavirus outbreak Adolescent Coronavirus disease 2019 (COVID-19) Neutrophils T-Lymphocytes Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Clinical Biochemistry Severity of Illness Index Monocytes Diagnosis Differential Leukocyte Count Hematology analyzer Internal medicine medicine Humans Medical physics Cell Population Data Child Respiratory Tract Infections Aged Retrospective Studies Biochemistry medical Aged 80 and over Automation Laboratory Hematology viral infection COVID-19 hematology leukocytes cell population data Platelet Count SARS-CoV-2 business.industry Biochemistry (medical) General Medicine Middle Aged C-Reactive Protein Multicenter study Erythrocyte Count Female Differential diagnosis business Biomarkers |
| Zdroj: | International Journal of Laboratory Hematology |
| ISSN: | 1751-553X 1751-5521 |
| DOI: | 10.1111/ijlh.13368 |
| Popis: | Introduction: Cell population data (CPD) are background optical signals measured during complete blood count analysis on hematology analyzers that reflect structural and morphological characteristics of leukocytes. Our aim was to assess the value of CPD obtained on Sysmex XN-1000 in the differential diagnosis of coronavirus disease 2019 (COVID-19) at the early stage of the disease. Methods: This retrospective study included 114 COVID-19 confirmed cases and 88 negative patients presenting with respiratory flu-like symptoms for whom laboratory analysis was performed at hospital admission. Results of leukocyte count, including CPD, and C-reactive protein (CRP) were compared between the two groups. Results: All CPD except lymphocyte internal complexity (LY-WX) and monocyte nucleic acid content (MO- WY) were significantly different in COVID-19 compared to non-COVID-19 cases (P |
| Databáze: | OpenAIRE |
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