Disorganization of the Retinal Inner Layers after Anti-VEGF Treatment for Macular Edema due to Branch Retinal Vein Occlusion
| Autor: | Hisako Hayashi, Eri Nakano, Toru Ota, Isao Nakata, Yoko Jingami, Kenji Yamashiro |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Vascular Endothelial Growth Factor A
medicine.medical_specialty Visual acuity genetic structures Fundus Oculi Recombinant Fusion Proteins Angiogenesis Inhibitors Drug Administration Schedule Macular Edema chemistry.chemical_compound Optical coherence tomography Ophthalmology Ranibizumab Retinal Vein Occlusion medicine Macula Lutea Fluorescein Angiography Macular edema Retrospective Studies medicine.diagnostic_test Dose-Response Relationship Drug business.industry Retinal General Medicine medicine.disease eye diseases Sensory Systems Receptors Vascular Endothelial Growth Factor Treatment Outcome chemistry Baseline characteristics Intravitreal Injections Branch retinal vein occlusion sense organs Anti vegf treatment medicine.symptom business Tomography Optical Coherence Follow-Up Studies |
| Zdroj: | Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde. 240(4) |
| ISSN: | 1423-0267 |
| Popis: | Purpose: To evaluate the association between disorganization of the retinal inner layers (DRIL) and visual acuity (VA) after anti-VEGF treatment for macular edema (ME) due to branch retinal vein occlusion (BRVO). Methods: Sixty eyes of 60 patients were retrospectively investigated. Baseline characteristics and factors analyzed on optical coherence tomography (OCT) examination at the final visit were evaluated in association with VA at the final visit. Results: DRIL was detected in 39 eyes at the final visit. The central subfield thickness was significantly higher in the eyes with DRIL. While DRIL length at the final visit showed a significant association with final VA on univariable analysis, only age and ellipsoid zone disruption on OCT at the final visit were found to be significantly associated with VA on multivariable analysis. Conclusions: DRIL had only a minor role in determining VA after anti-VEGF treatment for ME due to BRVO. |
| Databáze: | OpenAIRE |
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