Impact of irradiation setup in proton spot scanning brain therapy on organ doses from secondary radiation

Autor: Anna M. Flejmer, Irena Gudowska, Alexandru Dasu, Oscar Ardenfors
Rok vydání: 2017
Předmět:
Adult
Male
Materials science
Proton
Quantitative Biology::Tissues and Organs
Physics::Medical Physics
Monte Carlo method
Radiation
Radiation Dosage
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Proton Therapy
Humans
Radiology
Nuclear Medicine and imaging
Irradiation
Child
Radiometry
Proton therapy
Spot scanning
Lateral field
Neutrons
Photons
Radiological and Ultrasound Technology
business.industry
Brain Neoplasms
Phantoms
Imaging
Radiotherapy Planning
Computer-Assisted
Public Health
Environmental and Occupational Health
Brain
Dose-Response Relationship
Radiation
Radiotherapy Dosage
General Medicine
030220 oncology & carcinogenesis
Secondary radiation
Physics::Accelerator Physics
Female
Protons
Nuclear medicine
business
Tomography
X-Ray Computed
Monte Carlo Method
Zdroj: Radiation protection dosimetry. 180(1-4)
ISSN: 1742-3406
Popis: A Monte Carlo model of a proton spot scanning pencil beam was used to simulate organ doses from secondary radiation produced from brain tumour treatments delivered with either a lateral field or a vertex field to one adult and one paediatric patient. Absorbed doses from secondary neutrons, photons and protons and neutron equivalent doses were higher for the vertex field in both patients, but the differences were low in absolute terms. Absorbed doses ranged between 0.1 and 43 μGy.Gy-1 in both patients with the paediatric patient receiving higher doses. The neutron equivalent doses to the organs ranged between 0.5 and 141 μSv.Gy-1 for the paediatric patient and between 0.2 and 134 μSv.Gy-1 for the adult. The highest neutron equivalent dose from the entire treatment was 7 mSv regardless of field setup and patient size. The results indicate that different field setups do not introduce large absolute variations in out-of-field doses produced in patients undergoing proton pencil beam scanning of centrally located brain tumours.
Databáze: OpenAIRE
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